Target APC100193

Local target id
>gnl|sha|A0L4iuWz2y5c7HQRzS16TXEshUw|210007|210007.000|complement|1531430|1532863  
Stage
in_pdb   PDB:
Locus Tag/Selection DB Lookup
SMU.1601  
NCBI Protein Lookup
gi: 24379982   accession: NP_721937  
Organism
Streptococcus mutans UA159  
Common Name
6-phospho-beta-glucosidase [Streptococcus mutans UA159]  
Gene Name
celA  
NCBI Gene Lookup
1028834  
NCBI Annotation
converts 6-phospho-beta-D-glucosyl-(1,4)-D-glucose to glucose and glucose 6-phosphate; required for cellobiose uptake and metabolism  
Selection Phase
MCSG::Biology::Human Microbiome  
Date Approved
Oct 05, 2010  
Justification for Selection
Glycosyl hydrolases with unknown structure  
Priority
1  
Sequence Length
477  
(Subtargets)
 
Molecular Weight
55.1 kDa  
Sequence
MSKLPENFLW GGAVAAHQLE GGWQEGGKGI SVADVMTAGR HGVAREITAG VLEGKYYPNH EAIDFYHHYK EDVKLFAEMG FKCFRTSIAW TRIFPKGDEA EPNEAGLQFY DDLFDECLKY GIEPVVTLSH FELPYHLVTE YGGFTNRKVI DFFVHFAEVC FRRYKDKVKY WMTFNEINNQ ANYQEDFAPF TNSGIVYKEG DDREAIMYQA AHYELVASAR AVKIGHAINP NLNIGCMVAM CPIYPATCNP KDILMAQKAM QKRYYFADVH VHGFYPEHIF KYWERKAIKV DFTERDKKDL FEGTVDYIGF SYYMSFVIDA HRENNPYYDY LETEDLVKNP YVKASDWDWQ IDPQGLRYAL NWFTDMYHLP LFIVENGFGA IDQVEADGMV HDDYRIDYLG AHIKEMIKAV DEDGVELMGY TPWGCIDLVS AGTGEMRKRY GFIYVDKDDE GKGTLKRSPK LSFNWYKEVI ASNGDDI  
DNA Sequence
ATGTCT AAATTA CCTGAA AATTTT CTCTGG GGCGGT GCGGTT GCTGCC CATCAG CTAGAA GGCGGT TGGCAA GAAGGA GGCAAG GGAATT TCTGTT GCTGAT GTCATG ACTGCT GGTCGG CACGGC GTTGCG CGTGAA ATCACA GCCGGT GTTCTA GAAGGT AAGTAT TATCCT AACCAT GAAGCC ATTGAT TTTTAT CATCAC TATAAA GAAGAT GTCAAA TTGTTT GCCGAA ATGGGC TTCAAA TGTTTT CGGACT TCCATC GCTTGG ACACGG ATTTTT CCTAAG GGAGAT GAAGCA GAGCCT AATGAA GCAGGT CTGCAA TTTTAT GATGAC CTTTTT GATGAA TGTCTG AAATAT GGTATT GAACCC GTTGTG ACCCTA TCGCAT TTTGAA TTGCCT TATCAC CTTGTT ACCGAA TATGGT GGCTTT ACTAAC CGAAAA GTAATT GATTTC TTTGTT CATTTT GCTGAA GTTTGC TTTCGT CGTTAT AAGGAT AAGGTT AAGTAT TGGATG ACTTTC AACGAA ATCAAT AACCAA GCCAAT TATCAA GAAGAT TTTGCA CCTTTT ACTAAT TCGGGG ATTGTT TACAAA GAGGGA GATGAC CGCGAA GCGATT ATGTAC CAAGCT GCTCAT TATGAA CTGGTA GCTTCT GCGCGT GCCGTT AAAATT GGTCAT GCGATT AATCCC AATCTC AATATT GGGTGC ATGGTT GCCATG TGTCCA ATTTAT CCAGCA ACCTGT AACCCT AAAGAT ATCCTC ATGGCT CAAAAA GCTATG CAAAAG CGTTAT TACTTT GCGGAT GTTCAT GTCCAT GGTTTT TATCCA GAACAT ATTTTC AAGTAT TGGGAA CGCAAG GCTATT AAGGTT GATTTT ACTGAG CGAGAT AAGAAG GATTTG TTTGAA GGAACG GTAGAT TACATC GGCTTT TCATAT TACATG TCCTTT GTCATT GATGCT CACCGT GAAAAT AATCCT TACTAT GATTAT CTAGAA ACAGAA GATTTA GTTAAA AATCCT TATGTA AAGGCT TCTGAC TGGGAT TGGCAA ATAGAT CCTCAA GGTTTG CGTTAT GCTCTC AATTGG TTTACT GACATG TATCAT TTACCG CTTTTC ATTGTT GAGAAT GGCTTT GGAGCC ATTGAT CAAGTT GAAGCT GATGGC ATGGTT CACGAC GATTAT CGGATT GATTAT CTGGGT GCTCAT ATCAAG GAGATG ATTAAG GCTGTT GATGAA GATGGC GTTGAG CTCATG GGCTAT ACACCT TGGGGA TGTATT GATCTG GTTTCA GCAGGA ACAGGT GAAATG CGCAAG CGCTAC GGTTTT ATTTAT GTTGAT AAGGAC GATGAA GGCAAG GGAACC CTCAAA CGTTCA CCAAAA TTATCA TTCAAT TGGTAT AAAGAA GTCATT GCTTCA AATGGA GATGAC ATTTAA  
Community nominated
False  
Partnership nominated
 
Biomedical
True  
Metagenomic
True  
Structural coverage
True  
Psi 2
False