Midwest Center for Structural Genomics


MCSG ID	Priority	stage	Locus Tag	NCBI GI	Gene Name	Common Name	Sequence Length	Justification	Project	Homolog PDB ID	Homolog Sequence Identity	Target Organism	Request Person
APC102184 (show subtarget assignments)	1	in_pdb 3OWC		15597774		unnamed protein product [Pseudomonas ae...	186		MCSG::Biology::Pathogens	2VI7	27.4%	Pseudomonas aeruginosa

APC101324 (show subtarget assignments)	1	soluble	Plim_3573	296016147		DNA methylase N-4/N-6 domain protein [Pl...	306		MCSG::Coverage::GEBA	1EG2	27.5%	Planctomyces limnophilus

APC102522 (show subtarget assignments)	3	expression_tested		112360123		putative multifunctional Cca protein	372		CONS::PCSEP::Effectors	3H37	27.5%	Campylobacter jejuni

APC110766 (show subtarget assignments)	1	soluble		258653307		iron hydroxamate ABC transporter peripla...	346		MCSG::Coverage::SBP	2X4L	27.5%	Nakamurella multipartita

APC103635 (show subtarget assignments)	1	in_crystallization_trials		255346804		DegT/DnrJ/EryC1/StrS aminotransferase [P...	436		MCSG::Coverage::GEBA	3BN1	27.5%	Pedobacter heparinus

APC103368 (show subtarget assignments)	1	expression_tested		257798384		transcriptional regulator, LysR family [...	304		MCSG::Coverage::GEBA	2H98	27.5%	Desulfohalobium retbaense

APC104207 (show subtarget assignments)	1	selected		0			484		MCSG::Technology::Complexes	4H3T	27.5%	Saccharomonospora viridis

APC104167 (show subtarget assignments)	1	expression_tested		0			484		COMM::NCBI::CRISPR	4H3T	27.5%	Saccharomonospora viridis

APC100430 (show subtarget assignments)	1	crystallized	Dtox_0342	257777401		cobyrinic acid ac-diamide synthase [Desu...	259		MCSG::Coverage::GEBA	3KJE	27.5%	Desulfotomaculum acetoxidans

APC109655 (show subtarget assignments)	7	selected		228925025		bthur0011_59050	545		CONS::NATPRO::Enzymes	1RQG	27.5%	Streptomyces spiroverticillatus

APC108807 (show subtarget assignments)	1	soluble		150955149		putative periplasmic binding protein/Lac...	353		MCSG::Biology::Human Microbiome	3H5O	27.5%	Klebsiella pneumoniae

APC112007 (show subtarget assignments)	9	purified		15610077		multifunctional mycocerosic acid synthas...	2111		CONS::MTBI::Essential Enzymes	5BP1	27.5%	Mycobacterium tuberculosis

APC106877 (show subtarget assignments)	7	expression_tested		16804183		hypothetical protein lmo2144 [Listeria m...	244		COMM::IIT::Listeria.TF	2WV0	27.5%	Listeria monocytogenes

APC110138 (show subtarget assignments)	1	purified		15613600		iron (III) dicitrate transporter permeas...	341		MCSG::Coverage::SBP	3EIW	27.5%	Bacillus halodurans

APC110432 (show subtarget assignments)	1	expression_tested		284044845		glycosyl transferase family protein [Con...	662		MCSG::Biology::Essential Enzymes	3UDF	27.5%	Conexibacter woesei

APC110403 (show subtarget assignments)	1	expression_tested		283946948		na	356		MCSG::Coverage::GEBA	4YV7	27.5%	Conexibacter woesei

APC108832 (show subtarget assignments)	1	selected		125714195		extracellular solute-binding protein fam...	269		MCSG::Biology::Human Microbiome	4PRS	27.5%	Ruminiclostridium thermocellum

APC103071 (show subtarget assignments)	1	expression_tested		229565350		extracellular solute-binding protein fam...	441		MCSG::Coverage::GEBA	3OO6	27.5%	Beutenbergia cavernae

APC109884 (show subtarget assignments)	7	in_crystallization_trials		228925025		bthur0011_59050	545		CONS::NATPRO::Enzymes	1RQG	27.5%	Bacillus thuringiensis

APC113181 (show subtarget assignments)	8	in_crystallization_trials		494844830			506		COMM::WSU::GH	4L7T	27.5%	Bacteroides coprocola

APC110271 (show subtarget assignments)	1	expression_tested		206563339		putative penicillin-binding protein [Bur...	843		MCSG::Biology::Essential Enzymes	3UDF	27.5%	Burkholderia cenocepacia

APC113068 (show subtarget assignments)	1	soluble		256035323		na	280		MCSG::Coverage::GEBA	4ZI5	27.5%	Chitinophaga pinensis

APC109641 (show subtarget assignments)	7	selected		159460279		TtmM	353		CONS::NATPRO::Enzymes	5EQN	27.5%	Streptomyces spiroverticillatus

APC100102 (show subtarget assignments)	1	purified	c5124	26250934		alpha-galactosidase [Escherichia coli CF...	451		MCSG::Biology::Human Microbiome	1S6Y	27.6%	Escherichia coli

APC109495 (show subtarget assignments)	7	selected		33327095		FdmE	141		CONS::NATPRO::Enzymes	2H0V	27.6%	Streptomyces griseochromogenes

APC103775 (show subtarget assignments)	1	expression_tested		269786736		HAD-superfamily subfamily IB hydrolase, ...	217		MCSG::Coverage::GEBA	3FVV	27.6%	Sphaerobacter thermophilus

APC109527 (show subtarget assignments)	7	selected		5002550		NonR	279		CONS::NATPRO::Enzymes	5FRD	27.6%	Streptomyces griseus

APC103652 (show subtarget assignments)	1	soluble		255344141		DNA polymerase III, delta subunit [Pedob...	341		MCSG::Coverage::GEBA	3ZH9	27.6%	Pedobacter heparinus

APC105810 (show subtarget assignments)	9	selected		9951199		hypothetical protein	307		CONS::PCSEP::Effectors	3KVN	27.6%	Pseudomonas aeruginosa

APC104211 (show subtarget assignments)	1	selected		257055431		CRISPR-associated protein, Cse3 family	197		MCSG::Technology::Complexes	1VY8	27.6%	Saccharomonospora viridis

APC109872 (show subtarget assignments)	7	selected		32492539		AAP85357	411		CONS::NATPRO::Enzymes	2X3N	27.6%	Streptomyces griseoruber

APC101356 (show subtarget assignments)	1	expression_tested	Taci_0057	269099310		periplasmic solute binding protein [Ther...	276		MCSG::Coverage::GEBA	2OV1	27.6%	Thermanaerovibrio acidaminovorans

APC110936 (show subtarget assignments)	1	expression_tested		146276175		1A family penicillin-binding protein [Rh...	788		MCSG::Biology::Essential Enzymes	4OON	27.6%	Rhodobacter sphaeroides

APC101927 (show subtarget assignments)	9	selected		267993125		chorismate mutase [Salmonella enterica s...	181		CONS::PCSEP::Effectors	2GBB	27.6%	Salmonella enterica

APC102434 (show subtarget assignments)	1	expression_tested		85776231		Sel1	261		MCSG::Biology::Type IV orthologs	5GAO	27.6%	Anaeromyxobacter dehalogenans

APC108947 (show subtarget assignments)	1	expression_tested		150954860		putative bacterial extracellular solute-...	276		MCSG::Biology::Human Microbiome	4ZV1	27.6%	Klebsiella pneumoniae

APC111312 (show subtarget assignments)	1	in_crystallization_trials		229566019		na	560		MCSG::Coverage::GEBA	5MKK	27.6%	Beutenbergia cavernae

APC102131 (show subtarget assignments)	1	in_crystallization_trials	RSP_0613	77388602		conserved hypothetical protein [Rhodobac...	170		MCSG::Biology::Pathogens	1WK4	27.6%	Rhodobacter sphaeroides

APC111078 (show subtarget assignments)	1	expression_tested		269836324		glycosyl transferase family protein [Sph...	811		MCSG::Biology::Essential Enzymes	4OON	27.6%	Sphaerobacter thermophilus

APC111292 (show subtarget assignments)	1	expression_tested		113473957		FHA modulated glycosyl transferase/trans...	762		MCSG::Biology::Essential Enzymes	5U2G	27.6%	Trichodesmium erythraeum

APC111129 (show subtarget assignments)	7	purified		87161334		hypothetical protein SAUSA300_0289 [Stap...	163		COMM::UofChicago::B. anthracis	3I0T	27.6%	Staphylococcus aureus

APC102411 (show subtarget assignments)	1	soluble		85773967		Methyltransferase type 11	210		MCSG::Biology::Type IV orthologs	3OU2	27.6%	Anaeromyxobacter dehalogenans

APC109829 (show subtarget assignments)	7	selected		22255853		AAM94778	297		CONS::NATPRO::Enzymes	2FYT	27.6%	Micromonospora echinospora

APC100695 (show subtarget assignments)	1	soluble	Sthe_0262	269785558		amidohydrolase [Sphaerobacter thermophil...	478		MCSG::Coverage::GEBA	4V1X	27.6%	Sphaerobacter thermophilus

APC111439 (show subtarget assignments)	9	selected		0		NULL	124		CONS::UC4CDI::CT-CDI.Complexes	5X7E	27.6%	Escherichia coli

APC101552 (show subtarget assignments)	7	soluble	STM1269	16419785		putative chorismate mutase [Salmonella e...	181		CONS::PCSEP::Effectors	2GBB	27.6%	Salmonella enterica

APC103683 (show subtarget assignments)	1	in_crystallization_trials		256587193		transcriptional regulator, tetR family [...	195		MCSG::Coverage::GEBA	3VPR	27.6%	Saccharomonospora viridis

APC100220 (show subtarget assignments)	1	expression_tested	SSO2534	15899268		cellulase (endo 1,4 beta glucanase), put...	322		MCSG::Biology::Human Microbiome	3VGI	27.7%	Sulfolobus solfataricus

APC101170 (show subtarget assignments)	1	soluble	Hmuk_1086	257169454		rhodopsin [Halomicrobium mukohataei DSM ...	234		MCSG::Coverage::GEBA	2KSY	27.7%	Halomicrobium mukohataei

APC109742 (show subtarget assignments)	7	selected		83320231		ABC02796	195		CONS::NATPRO::Enzymes	1UFK	27.7%	Actinomadura sp.

APC101074 (show subtarget assignments)	1	soluble	Apre_0428	256797820		pyridoxal/pyridoxine/pyridoxamine kinase...	250		MCSG::Coverage::GEBA	3MBH	27.7%	Anaerococcus prevotii

APC103570 (show subtarget assignments)	1	in_pdb 5J7M		283810160		Cupin 2 conserved barrel domain protein ...	130		MCSG::Coverage::GEBA	4RD7	27.7%	Kribbella flavida

APC103364 (show subtarget assignments)	1	expression_tested		257797669		methyltransferase GidB [Desulfohalobium ...	219		MCSG::Coverage::GEBA	3G88	27.7%	Desulfohalobium retbaense

APC107022 (show subtarget assignments)	1	in_pdb 4E2G		269787601		Cupin 2 conserved barrel domain protein ...	123		MCSG::Coverage::GEBA	2PFW	27.7%	Sphaerobacter thermophilus

APC110606 (show subtarget assignments)	1	expression_tested		262195182		peptidoglycan glycosyltransferase [Halia...	708		MCSG::Biology::Essential Enzymes	3OC2	27.7%	Haliangium ochraceum

APC102027 (show subtarget assignments)	3	expression_tested	PD_0062	28056059		fimbrial subunit precursor [Xylella fast...	184		CONS::PCSEP::Effectors	3JWN	27.7%	Xylella fastidiosa

APC100346 (show subtarget assignments)	1	in_pdb 4XEA	Aaci_1020	257477739		peptidase M16 domain protein [Alicycloba...	429		MCSG::Coverage::GEBA	3EOQ	27.7%	Alicyclobacillus acidocaldarius

APC103692 (show subtarget assignments)	1	soluble		269098235		ABC-type sugar transport system, peripla...	431		MCSG::Coverage::GEBA	3VXB	27.7%	Sanguibacter keddieii

APC100780 (show subtarget assignments)	1	in_pdb 3RNR	Taci_1699	269100926		Stage II sporulation E family protein [T...	208		MCSG::Coverage::GEBA	2J82	27.7%	Thermanaerovibrio acidaminovorans

APC108871 (show subtarget assignments)	1	expression_tested		150955205		NADH dehydrogenase transcriptional regul...	297		MCSG::Biology::Human Microbiome	3HHG	27.7%	Klebsiella pneumoniae

APC100034 (show subtarget assignments)	1	expression_tested	BT_4149	29349557		exo-poly-alpha-D-galacturonosidase [Bact...	352		MCSG::Biology::Human Microbiome	2UVE	27.7%	Bacteroides thetaiotaomicron

APC102101 (show subtarget assignments)	1	in_pdb 3UO3 3UO2		45270848		YGL018C [Saccharomyces cerevisiae].	184		MCSG::Biology::Pathogens	3HHO	27.7%	Saccharomyces cerevisiae

APC110889 (show subtarget assignments)	1	expression_tested		28869702		penicillin-binding protein [Pseudomonas ...	629		MCSG::Biology::Essential Enzymes	3OC2	27.7%	Pseudomonas syringae

APC102157 (show subtarget assignments)	1	soluble	VP0521	28897295		fused phosphoenolpyruvate-protein phosph...	748		MCSG::Biology::Pathogens	2HRO	27.7%	Vibrio parahaemolyticus

APC101230 (show subtarget assignments)	1	expression_tested	Lebu_1496	257050186		extracellular solute-binding protein fam...	405		MCSG::Coverage::GEBA	5F7V	27.7%	Leptotrichia buccalis

APC100371 (show subtarget assignments)	1	soluble	Apre_1006	256798379		Arginine decarboxylase [Anaerococcus pre...	445		MCSG::Coverage::GEBA	2X3L	27.7%	Anaerococcus prevotii

APC110983 (show subtarget assignments)	1	purified		99081857		peptidoglycan glycosyltransferase [Ruege...	593		MCSG::Biology::Essential Enzymes	3EQU	27.7%	Ruegeria sp.

APC110216 (show subtarget assignments)	1	expression_tested		119025461		solute binding protein of ABC transporte...	433		MCSG::Coverage::SBP	4GNR	27.7%	Bifidobacterium adolescentis

APC113401 (show subtarget assignments)	1	expression_tested		478764802			155		MCSG::Coverage::FunFam	4CRM	27.7%	Thermoplasmatales archaeon

APC110486 (show subtarget assignments)	1	in_pdb 4MLC 4Q6B		219666180		ABC transporter substrate-binding protei...	380		MCSG::Coverage::SBP	1USG	27.7%	Desulfitobacterium hafniense

APC110004 (show subtarget assignments)	1	expression_tested		256372346		solute-binding protein [Acidimicrobium f...	404		MCSG::Coverage::SBP	3M9W	27.7%	Acidimicrobium ferrooxidans

APC108636 (show subtarget assignments)	5	selected		15595282		unnamed protein product [Pseudomonas aer...	498		COMM::HARVARD::TypeVI	3J9O	27.7%	Pseudomonas aeruginosa

APC110262 (show subtarget assignments)	1	expression_tested		27379330		unnamed protein product [Bradyrhizobium ...	217		MCSG::Biology::Essential Enzymes	4LZH	27.7%	Bradyrhizobium diazoefficiens

APC103716 (show subtarget assignments)	1	expression_tested		268616407		HAD-superfamily hydrolase, subfamily IIB...	278		MCSG::Coverage::GEBA	1NF2	27.7%	Sebaldella termitidis

APC116085 (show subtarget assignments)	1	expression_tested		1			489		CONS::NATPRO::Enzymes	5UGQ	27.8%	root

APC103750 (show subtarget assignments)	1	in_pdb 4MOZ		256792323		fructose-bisphosphate aldolase [Slackia ...	313		MCSG::Coverage::GEBA	1OJX	27.8%	Slackia heliotrinireducens

APC103568 (show subtarget assignments)	1	expression_tested		283810275		conserved hypothetical protein [Kribbell...	255		MCSG::Coverage::GEBA	4QN9	27.8%	Kribbella flavida

APC100241 (show subtarget assignments)	1	in_pdb 3UPS	ZMO1663	56552559		iojap-like protein [Zymomonas mobilis su...	133		MCSG::Biology::Human Microbiome	2O5A	27.8%	Zymomonas mobilis

APC100033 (show subtarget assignments)	1	in_pdb 5C0P	BT_1873	29347283		endo-arabinase [Bacteroides thetaiotaomi...	327		MCSG::Biology::Human Microbiome	4QQS	27.8%	Bacteroides thetaiotaomicron

APC100304 (show subtarget assignments)	1	crystallized	Aaci_2155	257478845		Xylose isomerase domain protein TIM barr...	322		MCSG::Coverage::GEBA	2ZDS	27.8%	Alicyclobacillus acidocaldarius

APC106818 (show subtarget assignments)	7	in_crystallization_trials		16802535		hypothetical protein lmo0492 [Listeria m...	302		COMM::IIT::Listeria.TF	3FZV	27.8%	Listeria monocytogenes

APC108883 (show subtarget assignments)	1	soluble		213524750		regulatory protein, LacI	338		MCSG::Biology::Human Microbiome	1BDI	27.8%	Bifidobacterium longum

APC110143 (show subtarget assignments)	1	in_crystallization_trials		15615135		stage V sporulation protein [Bacillus ha...	644		MCSG::Biology::Essential Enzymes	3EQU	27.8%	Bacillus halodurans

APC100708 (show subtarget assignments)	1	in_pdb 3R0V	Sthe_2971	269788233		alpha/beta hydrolase fold protein [Sphae...	259		MCSG::Coverage::GEBA	2XUA	27.8%	Sphaerobacter thermophilus

APC105844 (show subtarget assignments)	3	purified		34103893		probable secreted protein EspA [Chromoba...	184		CONS::PCSEP::Effectors	1XOU	27.8%	Chromobacterium violaceum

APC109357 (show subtarget assignments)	7	selected		410025766		KedU21	352		CONS::NATPRO::Enzymes	3O04	27.8%	Streptoalloteichus sp.

APC110247 (show subtarget assignments)	1	expression_tested		27379174		hypothetical protein [Bradyrhizobium jap...	389		MCSG::Coverage::SBP	3H75	27.8%	Bradyrhizobium diazoefficiens

APC107197 (show subtarget assignments)	1	soluble		257168746		metallophosphoesterase [Halomicrobium mu...	187		MCSG::Coverage::GEBA	1XM7	27.8%	Halomicrobium mukohataei

APC106924 (show subtarget assignments)	3	selected		15239263		concanavalin A-like lectin kinase-like p...	288		COMM::UofMissouri::Factors	5AVA	27.8%	Arabidopsis thaliana

APC105973 (show subtarget assignments)	9	soluble		15607533		ndhA gene product [Mycobacterium tubercu...	470		CONS::MTBI::Essential Enzymes	4G6G	27.9%	Mycobacterium tuberculosis

APC100010 (show subtarget assignments)	1	purified	AAur_3119	119961949		glycoside hydrolase family protein [Arth...	465		MCSG::Biology::Human Microbiome	1UYP	27.9%	Arthrobacter aurescens

APC116098 (show subtarget assignments)	1	soluble		1			241		CONS::NATPRO::Enzymes	1YW0	27.9%	root

APC109435 (show subtarget assignments)	7	selected		26541538		LnmL	86		CONS::NATPRO::Enzymes	2DNW	27.9%	Streptomyces atroolivaceus

APC103249 (show subtarget assignments)	1	selected		296021513		phosphopantothenoylcysteine decarboxylas...	416		MCSG::Coverage::GEBA	4QJI	27.9%	Cellulomonas flavigena

APC103241 (show subtarget assignments)	1	selected		296023275		HAD-superfamily hydrolase, subfamily IA,...	214		MCSG::Coverage::GEBA	3E58	27.9%	Cellulomonas flavigena

APC105804 (show subtarget assignments)	9	selected		9951045		conserved hypothetical protein	297		CONS::PCSEP::Effectors	4OTP	27.9%	Pseudomonas aeruginosa

APC109164 (show subtarget assignments)	7	selected		238626064		NosN [Streptomyces actuosus]	395		CONS::NATPRO::Enzymes	1OLT	27.9%	Streptomyces actuosus

APC111225 (show subtarget assignments)	1	purified		170078895		penicillin-binding protein [Synechococcu...	641		MCSG::Biology::Essential Enzymes	3OC2	27.9%	Synechococcus sp.

APC103105 (show subtarget assignments)	1	expression_tested		256558789		acetyltransferase (GNAT) family protein ...	328		MCSG::Coverage::GEBA	3TT2	27.9%	Brachybacterium faecium

APC101100 (show subtarget assignments)	1	crystallized	Dtox_2750	257779634		transcriptional regulator, Crp/Fnr famil...	222		MCSG::Coverage::GEBA	3FWE	27.9%	Desulfotomaculum acetoxidans

APC100302 (show subtarget assignments)	1	in_pdb 4OVJ	Aaci_2460	257479147		extracellular solute-binding protein fam...	441		MCSG::Coverage::GEBA	4R6K	27.9%	Alicyclobacillus acidocaldarius

APC100309 (show subtarget assignments)	1	expression_tested	Aaci_0788	257477512		Carbohydrate kinase, FGGY-like protein [...	441		MCSG::Coverage::GEBA	5VM1	27.9%	Alicyclobacillus acidocaldarius

APC100293 (show subtarget assignments)	1	in_pdb 3RAC	Aaci_0923	257477644		Histidine--tRNA ligase [Alicyclobacillus...	370		MCSG::Coverage::GEBA	3OD1	27.9%	Alicyclobacillus acidocaldarius

APC113667 (show subtarget assignments)	1	expression_tested		0			165		COMM::IASTATE::SoilCAZY	3GM8	27.9%	Mycobacterium sp.

APC100217 (show subtarget assignments)	1	soluble		21218824		alpha-galactosidase SCF8502 [Streptomyce...	499		MCSG::Biology::Human Microbiome	1ZY9	27.9%	Streptomyces coelicolor

APC108915 (show subtarget assignments)	1	soluble		213523024		periplasmic binding protein/LacI transcr...	337		MCSG::Biology::Human Microbiome	3DBI	27.9%	Bifidobacterium longum

APC100668 (show subtarget assignments)	1	expression_tested	Plim_1594	296014188		O-methyltransferase family 2 [Planctomyc...	387		MCSG::Coverage::GEBA	3GWZ	27.9%	Planctomyces limnophilus

APC110657 (show subtarget assignments)	1	purified		256833734		peptidoglycan glycosyltransferase [Jones...	764		MCSG::Biology::Essential Enzymes	4OON	27.9%	Jonesia denitrificans

APC106599 (show subtarget assignments)	1	soluble		0		conserved hypothetical protein	237		MCSG::Biology::Pathogens	4YC5	27.9%	Synechococcus sp.

APC113571 (show subtarget assignments)	1	expression_tested		0			165		COMM::IASTATE::SoilCAZY	3GM8	27.9%	Microbacterium sp.

APC101614 (show subtarget assignments)	9	selected		267994617		putative inner membrane protein [Salmon...	86		CONS::PCSEP::Effectors	4RQW	27.9%	Salmonella enterica

APC108632 (show subtarget assignments)	5	selected		37528063		hypothetical protein plu4227 [Photorhabd...	510		COMM::HARVARD::TypeVI	3J9O	27.9%	Photorhabdus luminescens

APC100760 (show subtarget assignments)	1	in_crystallization_trials	Sthe_1128	269786421		FAD-dependent pyridine nucleotide-disulp...	390		MCSG::Coverage::GEBA	3VRD	27.9%	Sphaerobacter thermophilus

APC107221 (show subtarget assignments)	1	purified		257170960		Electron transfer flavoprotein alpha/bet...	287		MCSG::Coverage::GEBA	4KPU	27.9%	Halomicrobium mukohataei

APC106824 (show subtarget assignments)	7	purified		16802654		hypothetical protein lmo0612 [Listeria m...	151		COMM::IIT::Listeria.TF	3BDD	27.9%	Listeria monocytogenes

APC103671 (show subtarget assignments)	1	crystallized		256587420		transcriptional regulator, RpiR family [...	333		MCSG::Coverage::GEBA	4IVN	27.9%	Saccharomonospora viridis

APC108934 (show subtarget assignments)	1	soluble		255345146		periplasmic binding protein/LacI transcr...	340		MCSG::Biology::Human Microbiome	3CTP	28%	Pedobacter heparinus

APC103637 (show subtarget assignments)	1	soluble		255343019		Thiamine-phosphate diphosphorylase [Pedo...	210		MCSG::Coverage::GEBA	1XI3	28%	Pedobacter heparinus

APC106665 (show subtarget assignments)	1	soluble		60495091		putative 2-oxoglutarate ferredoxin oxido...	616		MCSG::Biology::Pathogens	5B46	28%	Bacteroides fragilis

APC105720 (show subtarget assignments)	0	expression_tested		0			314		CONS::MTBI::Essential Enzymes	4X6G	28%	Mycobacterium tuberculosis

APC115024 (show subtarget assignments)	1	selected		189436857			879		MCSG::Biology::Human Microbiome	5TF0	28%	Bacteroides intestinalis

APC101012 (show subtarget assignments)	1	purified	Aaci_1878	257478571		transcriptional regulator, MarR family [...	158		MCSG::Coverage::GEBA	4NB5	28%	Alicyclobacillus acidocaldarius

APC109137 (show subtarget assignments)	8	expression_tested		28192467		NDP-hexose-4-ketoreductase [Streptomyces...	265		CONS::NATPRO::Enzymes	4TWR	28%	Streptomyces carzinostaticus

APC108607 (show subtarget assignments)	5	selected		206558748		putative type VI secretion system protei...	496		COMM::HARVARD::TypeVI	3J9O	28%	Burkholderia cenocepacia

APC113654 (show subtarget assignments)	1	soluble		0			150		COMM::IASTATE::SoilCAZY	1KWG	28%	Mycobacterium sp.

APC108781 (show subtarget assignments)	1	soluble		213524341		extracellular solute-binding protein, fa...	315		MCSG::Biology::Human Microbiome	4G4P	28%	Bifidobacterium longum

APC113558 (show subtarget assignments)	1	selected		0			150		COMM::IASTATE::SoilCAZY	1KWG	28%	Microbacterium sp.

APC103330 (show subtarget assignments)	1	selected		283947912		amidohydrolase 2 [Conexibacter woesei DS...	300		MCSG::Coverage::GEBA	3IRS	28%	Conexibacter woesei

APC105845 (show subtarget assignments)	3	purified		34103890		probable secreted protein EspA	186		CONS::PCSEP::Effectors	1XOU	28%	Chromobacterium violaceum

APC103091 (show subtarget assignments)	1	purified		229567202		molybdopterin-guanine dinucleotide biosy...	206		MCSG::Coverage::GEBA	1HJJ	28%	Beutenbergia cavernae

APC107274 (show subtarget assignments)	1	purified		257050919		chromosome segregation and condensation ...	207		MCSG::Coverage::GEBA	4I98	28%	Leptotrichia buccalis

APC100765 (show subtarget assignments)	1	expression_tested	Sthe_1744	269787035		peptidase S1 and S6 chymotrypsin/Hap [Sp...	282		MCSG::Coverage::GEBA	1Y8T	28%	Sphaerobacter thermophilus

APC106563 (show subtarget assignments)	1	soluble		0		hypothetical	118		MCSG::Biology::Pathogens	2CWY	28%	Synechococcus sp.

APC107012 (show subtarget assignments)	1	soluble		269785341		glycosyl transferase family 9 [Sphaeroba...	355		MCSG::Coverage::GEBA	3TOV	28%	Sphaerobacter thermophilus

APC111026 (show subtarget assignments)	1	soluble		269793871		transcriptional regulator [Sanguibacter ...	371		MCSG::Coverage::SBP	5UFH	28%	Sanguibacter keddieii

APC109084 (show subtarget assignments)	7	expression_tested		24575108		type II PCP [Streptomyces globisporus]	93		CONS::NATPRO::Enzymes	2MR7	28%	Streptomyces globisporus

APC113279 (show subtarget assignments)	9	soluble		397675289			243		COMM::SDDC	2YQZ	28%	Mycobacterium tuberculosis

APC102527 (show subtarget assignments)	3	in_crystallization_trials		112360078		putative HAD-superfamily hydrolase	212		CONS::PCSEP::Effectors	3FVV	28.1%	Campylobacter jejuni

APC110470 (show subtarget assignments)	1	expression_tested		110636601		glycosyltransferase [Cytophaga hutchinso...	762		MCSG::Biology::Essential Enzymes	3UDF	28.1%	Cytophaga hutchinsonii

APC110573 (show subtarget assignments)	1	expression_tested		238924608		peptidoglycan glycosyltransferase [Eubac...	530		MCSG::Biology::Essential Enzymes	4BJP	28.1%	Eubacterium rectale

APC103535 (show subtarget assignments)	1	soluble		283812872		phosphogluconate dehydrogenase, NAD-bind...	253		MCSG::Coverage::GEBA	5A9R	28.1%	Kribbella flavida

APC108402 (show subtarget assignments)	7	in_crystallization_trials		16262911		NodD3 nod box-dependent transcriptional ...	313		COMM::STANFORD::Nod-box	1UTB	28.1%	Sinorhizobium meliloti

APC100726 (show subtarget assignments)	1	in_pdb 4U4E	SPA3000	269785833		thiolase [Sphaerobacter thermophilus DSM...	383		MCSG::Coverage::GEBA	5AB4	28.1%	Sphaerobacter thermophilus

APC106535 (show subtarget assignments)	1	selected		39650631		pimeloyl-CoA dehydrogenase (small subuni...	380		MCSG::Biology::Pathogens	1BUC	28.1%	Rhodopseudomonas palustris

APC108777 (show subtarget assignments)	1	expression_tested		219536659		Dhaf_0331	542		MCSG::Biology::Human Microbiome	3RY3	28.1%	Desulfitobacterium hafniense

APC107414 (show subtarget assignments)	4	purified		15609352		dihydrolipoamide acetyltransferase [Myco...	553		CONS::MTBI::Essential Enzymes	3DUF	28.1%	Mycobacterium tuberculosis

APC100341 (show subtarget assignments)	1	in_pdb 4DZR	Aaci_2779	257479464		protein-(glutamine-N5) methyltransferase...	313		MCSG::Coverage::GEBA	1NV8	28.1%	Alicyclobacillus acidocaldarius

APC100197 (show subtarget assignments)	1	soluble	SAV_3019	29829561		beta-N-acetylhexosaminidase [Streptomyce...	534		MCSG::Biology::Human Microbiome	3TEV	28.1%	Streptomyces avermitilis

APC113042 (show subtarget assignments)	1	expression_tested		302150446		glycosyl hydrolase family 25	228		MCSG::Biology::Human Microbiome	1JFX	28.1%	Prevotella melaninogenica

APC103688 (show subtarget assignments)	1	expression_tested		269097975		metal-dependent hydrolase, beta-lactamas...	267		MCSG::Coverage::GEBA	1ZKP	28.1%	Sanguibacter keddieii

APC110441 (show subtarget assignments)	1	in_crystallization_trials		283950521		hypothetical protein	246		MCSG::Coverage::BIG-PFAM	3HQV	28.1%	Conexibacter woesei

APC116015 (show subtarget assignments)	9	soluble		0			448		CONS::NATPRO::Enzymes	2BVJ	28.1%

APC103452 (show subtarget assignments)	1	soluble		262078253		Haloacid dehalogenase domain protein hyd...	217		MCSG::Coverage::GEBA	4EX6	28.1%	Haliangium ochraceum

APC105886 (show subtarget assignments)	9	selected		13361541		IpaH-like protein [Escherichia coli O157...	167		CONS::PCSEP::Effectors	1G9U	28.1%	Escherichia coli

APC101195 (show subtarget assignments)	1	soluble	Hmuk_2602	257170949		cytochrome P450 [Halomicrobium mukohatae...	445		MCSG::Coverage::GEBA	5T6Q	28.2%	Halomicrobium mukohataei

APC105971 (show subtarget assignments)	9	purified		15610936		pks13 gene product [Mycobacterium tuberc...	1733		CONS::MTBI::Essential Enzymes	3TZW	28.2%	Mycobacterium tuberculosis

APC113426 (show subtarget assignments)	1	soluble		478765523			273		MCSG::Coverage::FunFam	4JC0	28.2%	Thermoplasmatales archaeon

APC103759 (show subtarget assignments)	1	purified		256792321		universal stress protein UspA-like prote...	147		MCSG::Coverage::GEBA	4WNY	28.2%	Slackia heliotrinireducens

APC109025 (show subtarget assignments)	7	expression_tested		83320235		N-glycosyltransferase	445		CONS::NATPRO::Enzymes	3OTG	28.2%	Actinomadura sp.

APC107158 (show subtarget assignments)	1	soluble		257476811		transcriptional regulator, XRE family [A...	262		MCSG::Coverage::GEBA	1S96	28.2%	Alicyclobacillus acidocaldarius

APC106644 (show subtarget assignments)	1	selected		132662865		coenzyme F420-reducing hydrogenase, delt...	174		MCSG::Biology::Pathogens	2E85	28.2%	Methanococcus maripaludis

APC101352 (show subtarget assignments)	1	soluble	Taci_0355	269099605		response regulator receiver modulated di...	464		MCSG::Coverage::GEBA	1W25	28.2%	Thermanaerovibrio acidaminovorans

APC102432 (show subtarget assignments)	1	expression_tested		85776112		putative circadian clock protein, KaiC	494		MCSG::Biology::Type IV orthologs	4O0M	28.2%	Anaeromyxobacter dehalogenans

APC103602 (show subtarget assignments)	1	expression_tested		258554003		transcriptional regulator, AsnC family [...	156		MCSG::Coverage::GEBA	2W25	28.2%	Nakamurella multipartita

APC108613 (show subtarget assignments)	5	selected		83721364		hypothetical protein BTH_I2963 [Burkhold...	496		COMM::HARVARD::TypeVI	3J9O	28.2%	Burkholderia thailandensis

APC108610 (show subtarget assignments)	5	selected		83716783		unnamed protein product [Burkholderia th...	508		COMM::HARVARD::TypeVI	3J9O	28.2%	Burkholderia thailandensis

APC103322 (show subtarget assignments)	1	selected		283951357		Cytosine deaminase [Conexibacter woesei ...	415		MCSG::Coverage::GEBA	4JNP	28.2%	Conexibacter woesei

APC103075 (show subtarget assignments)	1	purified		229567634		putative regulator [Beutenbergia caverna...	186		MCSG::Coverage::GEBA	3KKD	28.2%	Beutenbergia cavernae

APC107009 (show subtarget assignments)	1	expression_tested		269788007		transcriptional regulator, IclR family [...	270		MCSG::Coverage::GEBA	2G7U	28.2%	Sphaerobacter thermophilus

APC100527 (show subtarget assignments)	1	soluble	Lebu_1620	257050308		oxidoreductase domain protein [Leptotric...	326		MCSG::Coverage::GEBA	3E9M	28.2%	Leptotrichia buccalis

APC109123 (show subtarget assignments)	7	selected		164665143		type II beta-Tyr adenylation domain prot...	1115		CONS::NATPRO::Enzymes	4ZXJ	28.2%	Actinomadura madurae

APC110977 (show subtarget assignments)	1	soluble		99078287		LacI family transcription regulator [Rue...	362		MCSG::Coverage::SBP	3H5O	28.2%	Ruegeria sp.

APC109715 (show subtarget assignments)	7	selected		357415467		Sfla_6318	414		CONS::NATPRO::Enzymes	4K5R	28.2%	Streptomyces pratensis

APC103387 (show subtarget assignments)	1	in_pdb 4GBJ		254950143		6-phosphogluconate dehydrogenase NAD-bin...	294		MCSG::Coverage::GEBA	1YB4	28.2%	Dyadobacter fermentans

APC108801 (show subtarget assignments)	1	soluble		283814563		transcriptional regulator, LysR family	305		MCSG::Biology::Human Microbiome	2H98	28.2%	Spirosoma linguale

APC101194 (show subtarget assignments)	1	purified	Hmuk_2500	257170849		molybdenum cofactor biosynthesis protein...	335		MCSG::Coverage::GEBA	1TV7	28.3%	Halomicrobium mukohataei

APC103023 (show subtarget assignments)	1	selected		255923045		FAD dependent oxidoreductase [Actinosynn...	389		MCSG::Coverage::GEBA	4YSH	28.3%	Actinosynnema mirum

APC108735 (show subtarget assignments)	1	purified		238875128		transcriptional regulator (LacI family)	336		MCSG::Biology::Human Microbiome	1BDI	28.3%	Eubacterium rectale

APC112013 (show subtarget assignments)	9	soluble		15609368			364		CONS::MTBI::Essential Enzymes	1LC5	28.3%	Mycobacterium tuberculosis

APC107492 (show subtarget assignments)	3	soluble		15610645		hypothetical protein Rv3509c [Mycobacter...	515		CONS::MTBI::Essential Enzymes	4MQ5	28.3%	Mycobacterium tuberculosis

APC103556 (show subtarget assignments)	1	purified		283807802		Acyl-CoA synthetase (AMP-forming)/AMP-ac...	418		MCSG::Coverage::GEBA	4GR5	28.3%	Kribbella flavida

APC103543 (show subtarget assignments)	1	crystallized		283810767		modification methylase, HemK family [Kri...	262		MCSG::Coverage::GEBA	1NV8	28.3%	Kribbella flavida

APC103237 (show subtarget assignments)	1	expression_tested		296021138		Ribonuclease H [Cellulomonas flavigena D...	279		MCSG::Coverage::GEBA	2ETJ	28.3%	Cellulomonas flavigena

APC103360 (show subtarget assignments)	1	expression_tested		257798550		type IV pilus assembly protein PilM [Des...	325		MCSG::Coverage::GEBA	2YCH	28.3%	Desulfohalobium retbaense

APC103168 (show subtarget assignments)	1	expression_tested		256361643		acyl-CoA dehydrogenase domain protein [C...	381		MCSG::Coverage::GEBA	4M9A	28.3%	Catenulispora acidiphila

APC104209 (show subtarget assignments)	1	soluble		257055429		CRISPR-associated protein, Cse4 family	368		MCSG::Technology::Complexes	1VY8	28.3%	Saccharomonospora viridis

APC100343 (show subtarget assignments)	1	soluble	Aaci_0075	257476820		extracellular solute-binding protein fam...	441		MCSG::Coverage::GEBA	4QRZ	28.3%	Alicyclobacillus acidocaldarius

APC100328 (show subtarget assignments)	1	purified	Aaci_0913	257477634		extracellular solute-binding protein fam...	421		MCSG::Coverage::GEBA	4R9F	28.3%	Alicyclobacillus acidocaldarius

APC100477 (show subtarget assignments)	1	in_crystallization_trials	Dtox_1281	257778269		oxidoreductase FAD/NAD(P)-binding domain...	279		MCSG::Coverage::GEBA	4YLF	28.3%	Desulfotomaculum acetoxidans

APC102426 (show subtarget assignments)	1	expression_tested		85775448		Methyltransferase type 11	222		MCSG::Biology::Type IV orthologs	4C03	28.3%	Anaeromyxobacter dehalogenans

APC106624 (show subtarget assignments)	1	soluble		33566762		putative ring-hydroxylating dioxygenase ...	173		MCSG::Biology::Pathogens	3EN1	28.3%	Bordetella parapertussis

APC100413 (show subtarget assignments)	1	expression_tested	Dtox_3253	257780094		type IV pilus assembly protein PilM [Des...	350		MCSG::Coverage::GEBA	2YCH	28.3%	Desulfotomaculum acetoxidans

APC108861 (show subtarget assignments)	1	soluble		150955138		putative transcriptional regulator (LysR...	301		MCSG::Biology::Human Microbiome	3HHG	28.3%	Klebsiella pneumoniae

APC109179 (show subtarget assignments)	7	expression_tested		119433779		TlmVII [Streptoalloteichus hindustanus]	1141		CONS::NATPRO::Enzymes	4ZXJ	28.3%	Streptoalloteichus hindustanus

APC108745 (show subtarget assignments)	1	expression_tested		150955219		putative transcriptional regulator (LysR...	310		MCSG::Biology::Human Microbiome	3SZP	28.3%	Klebsiella pneumoniae

APC108737 (show subtarget assignments)	1	soluble		150955139		putative transcriptional regulator (LysR...	300		MCSG::Biology::Human Microbiome	3T1B	28.3%	Klebsiella pneumoniae

APC100823 (show subtarget assignments)	1	crystallized	Vpar_0360	269094053		beta-lactamase domain protein [Veillonel...	411		MCSG::Coverage::GEBA	1YCF	28.3%	Veillonella parvula

APC108888 (show subtarget assignments)	1	selected		125715215		transcriptional regulator, LacI family	342		MCSG::Biology::Human Microbiome	1RZR	28.3%	Ruminiclostridium thermocellum

APC107089 (show subtarget assignments)	1	soluble		257048783		Glutamyl-tRNA reductase [Leptotrichia bu...	346		MCSG::Coverage::GEBA	1GPJ	28.3%	Leptotrichia buccalis

APC111070 (show subtarget assignments)	1	soluble		269929012		Extracellular ligand-binding receptor [S...	375		MCSG::Coverage::SBP	3IP5	28.3%	Sphaerobacter thermophilus

APC102184
(show subtarget assignments)

1

in_pdb
3OWC

15597774

unnamed protein product [Pseudomonas ae...

186

MCSG::Biology::Pathogens

2VI7

27.4%

Pseudomonas aeruginosa

APC101324
(show subtarget assignments)

1

soluble

Plim_3573

296016147

DNA methylase N-4/N-6 domain protein [Pl...

306

MCSG::Coverage::GEBA

1EG2

27.5%

Planctomyces limnophilus

APC102522
(show subtarget assignments)

3

expression_tested

112360123

putative multifunctional Cca protein

372

CONS::PCSEP::Effectors

3H37

27.5%

Campylobacter jejuni

APC110766
(show subtarget assignments)

1

soluble

258653307

iron hydroxamate ABC transporter peripla...

346

MCSG::Coverage::SBP

2X4L

27.5%

Nakamurella multipartita

APC103635
(show subtarget assignments)

1

in_crystallization_trials

255346804

DegT/DnrJ/EryC1/StrS aminotransferase [P...

436

MCSG::Coverage::GEBA

3BN1

27.5%

Pedobacter heparinus

APC103368
(show subtarget assignments)

1

expression_tested

257798384

transcriptional regulator, LysR family [...

304

MCSG::Coverage::GEBA

2H98

27.5%

Desulfohalobium retbaense

APC104207
(show subtarget assignments)

1

selected

0

484

MCSG::Technology::Complexes

4H3T

27.5%

Saccharomonospora viridis

APC104167
(show subtarget assignments)

1

expression_tested

0

484

COMM::NCBI::CRISPR

4H3T

27.5%

Saccharomonospora viridis

APC100430
(show subtarget assignments)

1

crystallized

Dtox_0342

257777401

cobyrinic acid ac-diamide synthase [Desu...

259

MCSG::Coverage::GEBA

3KJE

27.5%

Desulfotomaculum acetoxidans

APC109655
(show subtarget assignments)

7

selected

228925025

bthur0011_59050

545

CONS::NATPRO::Enzymes

1RQG

27.5%

Streptomyces spiroverticillatus

APC108807
(show subtarget assignments)

1

soluble

150955149

putative periplasmic binding protein/Lac...

353

MCSG::Biology::Human Microbiome

3H5O

27.5%

Klebsiella pneumoniae

APC112007
(show subtarget assignments)

9

purified

15610077

multifunctional mycocerosic acid synthas...

2111

CONS::MTBI::Essential Enzymes

5BP1

27.5%

Mycobacterium tuberculosis

APC106877
(show subtarget assignments)

7

expression_tested

16804183

hypothetical protein lmo2144 [Listeria m...

244

COMM::IIT::Listeria.TF

2WV0

27.5%

Listeria monocytogenes

APC110138
(show subtarget assignments)

1

purified

15613600

iron (III) dicitrate transporter permeas...

341

MCSG::Coverage::SBP

3EIW

27.5%

Bacillus halodurans

APC110432
(show subtarget assignments)

1

expression_tested

284044845

glycosyl transferase family protein [Con...

662

MCSG::Biology::Essential Enzymes

3UDF

27.5%

Conexibacter woesei

APC110403
(show subtarget assignments)

1

expression_tested

283946948

na

356

MCSG::Coverage::GEBA

4YV7

27.5%

Conexibacter woesei

APC108832
(show subtarget assignments)

1

selected

125714195

extracellular solute-binding protein fam...

269

MCSG::Biology::Human Microbiome

4PRS

27.5%

Ruminiclostridium thermocellum

APC103071
(show subtarget assignments)

1

expression_tested

229565350

extracellular solute-binding protein fam...

441

MCSG::Coverage::GEBA

3OO6

27.5%

Beutenbergia cavernae

APC109884
(show subtarget assignments)

7

in_crystallization_trials

228925025

bthur0011_59050

545

CONS::NATPRO::Enzymes

1RQG

27.5%

Bacillus thuringiensis

APC113181
(show subtarget assignments)

8

in_crystallization_trials

494844830

506

COMM::WSU::GH

4L7T

27.5%

Bacteroides coprocola

APC110271
(show subtarget assignments)

1

expression_tested

206563339

putative penicillin-binding protein [Bur...

843

MCSG::Biology::Essential Enzymes

3UDF

27.5%

Burkholderia cenocepacia

APC113068
(show subtarget assignments)

1

soluble

256035323

na

280

MCSG::Coverage::GEBA

4ZI5

27.5%

Chitinophaga pinensis

APC109641
(show subtarget assignments)

7

selected

159460279

TtmM

353

CONS::NATPRO::Enzymes

5EQN

27.5%

Streptomyces spiroverticillatus

APC100102
(show subtarget assignments)

1

purified

c5124

26250934

alpha-galactosidase [Escherichia coli CF...

451

MCSG::Biology::Human Microbiome

1S6Y

27.6%

Escherichia coli

APC109495
(show subtarget assignments)

7

selected

33327095

FdmE

141

CONS::NATPRO::Enzymes

2H0V

27.6%

Streptomyces griseochromogenes

APC103775
(show subtarget assignments)

1

expression_tested

269786736

HAD-superfamily subfamily IB hydrolase, ...

217

MCSG::Coverage::GEBA

3FVV

27.6%

Sphaerobacter thermophilus

APC109527
(show subtarget assignments)

7

selected

5002550

NonR

279

CONS::NATPRO::Enzymes

5FRD

27.6%

Streptomyces griseus

APC103652
(show subtarget assignments)

1

soluble

255344141

DNA polymerase III, delta subunit [Pedob...

341

MCSG::Coverage::GEBA

3ZH9

27.6%

Pedobacter heparinus

APC105810
(show subtarget assignments)

9

selected

9951199

hypothetical protein

307

CONS::PCSEP::Effectors

3KVN

27.6%

Pseudomonas aeruginosa

APC104211
(show subtarget assignments)

1

selected

257055431

CRISPR-associated protein, Cse3 family

197

MCSG::Technology::Complexes

1VY8

27.6%

Saccharomonospora viridis

APC109872
(show subtarget assignments)

7

selected

32492539

AAP85357

411

CONS::NATPRO::Enzymes

2X3N

27.6%

Streptomyces griseoruber

APC101356
(show subtarget assignments)

1

expression_tested

Taci_0057

269099310

periplasmic solute binding protein [Ther...

276

MCSG::Coverage::GEBA

2OV1

27.6%

Thermanaerovibrio acidaminovorans

APC110936
(show subtarget assignments)

1

expression_tested

146276175

1A family penicillin-binding protein [Rh...

788

MCSG::Biology::Essential Enzymes

4OON

27.6%

Rhodobacter sphaeroides

APC101927
(show subtarget assignments)

9

selected

267993125

chorismate mutase [Salmonella enterica s...

181

CONS::PCSEP::Effectors

2GBB

27.6%

Salmonella enterica

APC102434
(show subtarget assignments)

1

expression_tested

85776231

Sel1

261

MCSG::Biology::Type IV orthologs

5GAO

27.6%

Anaeromyxobacter dehalogenans

APC108947
(show subtarget assignments)

1

expression_tested

150954860

putative bacterial extracellular solute-...

276

MCSG::Biology::Human Microbiome

4ZV1

27.6%

Klebsiella pneumoniae

APC111312
(show subtarget assignments)

1

in_crystallization_trials

229566019

na

560

MCSG::Coverage::GEBA

5MKK

27.6%

Beutenbergia cavernae

APC102131
(show subtarget assignments)

1

in_crystallization_trials

RSP_0613

77388602

conserved hypothetical protein [Rhodobac...

170

MCSG::Biology::Pathogens

1WK4

27.6%

Rhodobacter sphaeroides

APC111078
(show subtarget assignments)

1

expression_tested

269836324

glycosyl transferase family protein [Sph...

811

MCSG::Biology::Essential Enzymes

4OON

27.6%

Sphaerobacter thermophilus

APC111292
(show subtarget assignments)

1

expression_tested

113473957

FHA modulated glycosyl transferase/trans...

762

MCSG::Biology::Essential Enzymes

5U2G

27.6%

Trichodesmium erythraeum

APC111129
(show subtarget assignments)

7

purified

87161334

hypothetical protein SAUSA300_0289 [Stap...

163

COMM::UofChicago::B. anthracis

3I0T

27.6%

Staphylococcus aureus

APC102411
(show subtarget assignments)

1

soluble

85773967

Methyltransferase type 11

210

MCSG::Biology::Type IV orthologs

3OU2

27.6%

Anaeromyxobacter dehalogenans

APC109829
(show subtarget assignments)

7

selected

22255853

AAM94778

297

CONS::NATPRO::Enzymes

2FYT

27.6%

Micromonospora echinospora

APC100695
(show subtarget assignments)

1

soluble

Sthe_0262

269785558

amidohydrolase [Sphaerobacter thermophil...

478

MCSG::Coverage::GEBA

4V1X

27.6%

Sphaerobacter thermophilus

APC111439
(show subtarget assignments)

9

selected

0

NULL

124

CONS::UC4CDI::CT-CDI.Complexes

5X7E

27.6%

Escherichia coli

APC101552
(show subtarget assignments)

7

soluble

STM1269

16419785

putative chorismate mutase [Salmonella e...

181

CONS::PCSEP::Effectors

2GBB

27.6%

Salmonella enterica

APC103683
(show subtarget assignments)

1

in_crystallization_trials

256587193

transcriptional regulator, tetR family [...

195

MCSG::Coverage::GEBA

3VPR

27.6%

Saccharomonospora viridis

APC100220
(show subtarget assignments)

1

expression_tested

SSO2534

15899268

cellulase (endo 1,4 beta glucanase), put...

322

MCSG::Biology::Human Microbiome

3VGI

27.7%

Sulfolobus solfataricus

APC101170
(show subtarget assignments)

1

soluble

Hmuk_1086

257169454

rhodopsin [Halomicrobium mukohataei DSM ...

234

MCSG::Coverage::GEBA

2KSY

27.7%

Halomicrobium mukohataei

APC109742
(show subtarget assignments)

7

selected

83320231

ABC02796

195

CONS::NATPRO::Enzymes

1UFK

27.7%

Actinomadura sp.

APC101074
(show subtarget assignments)

1

soluble

Apre_0428

256797820

pyridoxal/pyridoxine/pyridoxamine kinase...

250

MCSG::Coverage::GEBA

3MBH

27.7%

Anaerococcus prevotii

APC103570
(show subtarget assignments)

1

in_pdb
5J7M

283810160

Cupin 2 conserved barrel domain protein ...

130

MCSG::Coverage::GEBA

4RD7

27.7%

Kribbella flavida

APC103364
(show subtarget assignments)

1

expression_tested

257797669

methyltransferase GidB [Desulfohalobium ...

219

MCSG::Coverage::GEBA

3G88

27.7%

Desulfohalobium retbaense

APC107022
(show subtarget assignments)

1

in_pdb
4E2G

269787601

Cupin 2 conserved barrel domain protein ...

123

MCSG::Coverage::GEBA

2PFW

27.7%

Sphaerobacter thermophilus

APC110606
(show subtarget assignments)

1

expression_tested

262195182

peptidoglycan glycosyltransferase [Halia...

708

MCSG::Biology::Essential Enzymes

3OC2

27.7%

Haliangium ochraceum

APC102027
(show subtarget assignments)

3

expression_tested

PD_0062

28056059

fimbrial subunit precursor [Xylella fast...

184

CONS::PCSEP::Effectors

3JWN

27.7%

Xylella fastidiosa

APC100346
(show subtarget assignments)

1

in_pdb
4XEA

Aaci_1020

257477739

peptidase M16 domain protein [Alicycloba...

429

MCSG::Coverage::GEBA

3EOQ

27.7%

Alicyclobacillus acidocaldarius

APC103692
(show subtarget assignments)

1

soluble

269098235

ABC-type sugar transport system, peripla...

431

MCSG::Coverage::GEBA

3VXB

27.7%

Sanguibacter keddieii

APC100780
(show subtarget assignments)

1

in_pdb
3RNR

Taci_1699

269100926

Stage II sporulation E family protein [T...

208

MCSG::Coverage::GEBA

2J82

27.7%

Thermanaerovibrio acidaminovorans

APC108871
(show subtarget assignments)

1

expression_tested

150955205

NADH dehydrogenase transcriptional regul...

297

MCSG::Biology::Human Microbiome

3HHG

27.7%

Klebsiella pneumoniae

APC100034
(show subtarget assignments)

1

expression_tested

BT_4149

29349557

exo-poly-alpha-D-galacturonosidase [Bact...

352

MCSG::Biology::Human Microbiome

2UVE

27.7%

Bacteroides thetaiotaomicron

APC102101
(show subtarget assignments)

1

in_pdb
3UO3
3UO2

45270848

YGL018C [Saccharomyces cerevisiae].

184

MCSG::Biology::Pathogens

3HHO

27.7%

Saccharomyces cerevisiae

APC110889
(show subtarget assignments)

1

expression_tested

28869702

penicillin-binding protein [Pseudomonas ...

629

MCSG::Biology::Essential Enzymes

3OC2

27.7%

Pseudomonas syringae

APC102157
(show subtarget assignments)

1

soluble

VP0521

28897295

fused phosphoenolpyruvate-protein phosph...

748

MCSG::Biology::Pathogens

2HRO

27.7%

Vibrio parahaemolyticus

APC101230
(show subtarget assignments)

1

expression_tested

Lebu_1496

257050186

extracellular solute-binding protein fam...

405

MCSG::Coverage::GEBA

5F7V

27.7%

Leptotrichia buccalis

APC100371
(show subtarget assignments)

1

soluble

Apre_1006

256798379

Arginine decarboxylase [Anaerococcus pre...

445

MCSG::Coverage::GEBA

2X3L

27.7%

Anaerococcus prevotii

APC110983
(show subtarget assignments)

1

purified

99081857

peptidoglycan glycosyltransferase [Ruege...

593

MCSG::Biology::Essential Enzymes

3EQU

27.7%

Ruegeria sp.

APC110216
(show subtarget assignments)

1

expression_tested

119025461

solute binding protein of ABC transporte...

433

MCSG::Coverage::SBP

4GNR

27.7%

Bifidobacterium adolescentis

APC113401
(show subtarget assignments)

1

expression_tested

478764802

155

MCSG::Coverage::FunFam

4CRM

27.7%

Thermoplasmatales archaeon

APC110486
(show subtarget assignments)

1

in_pdb
4MLC
4Q6B

219666180

ABC transporter substrate-binding protei...

380

MCSG::Coverage::SBP

1USG

27.7%

Desulfitobacterium hafniense

APC110004
(show subtarget assignments)

1

expression_tested

256372346

solute-binding protein [Acidimicrobium f...

404

MCSG::Coverage::SBP

3M9W

27.7%

Acidimicrobium ferrooxidans

APC108636
(show subtarget assignments)

5

selected

15595282

unnamed protein product [Pseudomonas aer...

498

COMM::HARVARD::TypeVI

3J9O

27.7%

Pseudomonas aeruginosa

APC110262
(show subtarget assignments)

1

expression_tested

27379330

unnamed protein product [Bradyrhizobium ...

217

MCSG::Biology::Essential Enzymes

4LZH

27.7%

Bradyrhizobium diazoefficiens

APC103716
(show subtarget assignments)

1

expression_tested

268616407

HAD-superfamily hydrolase, subfamily IIB...

278

MCSG::Coverage::GEBA

1NF2

27.7%

Sebaldella termitidis

APC116085
(show subtarget assignments)

1

expression_tested

1

489

CONS::NATPRO::Enzymes

5UGQ

27.8%

root

APC103750
(show subtarget assignments)

1

in_pdb
4MOZ

256792323

fructose-bisphosphate aldolase [Slackia ...

313

MCSG::Coverage::GEBA

1OJX

27.8%

Slackia heliotrinireducens

APC103568
(show subtarget assignments)

1

expression_tested

283810275

conserved hypothetical protein [Kribbell...

255

MCSG::Coverage::GEBA

4QN9

27.8%

Kribbella flavida

APC100241
(show subtarget assignments)

1

in_pdb
3UPS

ZMO1663

56552559

iojap-like protein [Zymomonas mobilis su...

133

MCSG::Biology::Human Microbiome

2O5A

27.8%

Zymomonas mobilis

APC100033
(show subtarget assignments)

1

in_pdb
5C0P

BT_1873

29347283

endo-arabinase [Bacteroides thetaiotaomi...

327

MCSG::Biology::Human Microbiome

4QQS

27.8%

Bacteroides thetaiotaomicron

APC100304
(show subtarget assignments)

1

crystallized

Aaci_2155

257478845

Xylose isomerase domain protein TIM barr...

322

MCSG::Coverage::GEBA

2ZDS

27.8%

Alicyclobacillus acidocaldarius

APC106818
(show subtarget assignments)

7

in_crystallization_trials

16802535

hypothetical protein lmo0492 [Listeria m...

302

COMM::IIT::Listeria.TF

3FZV

27.8%

Listeria monocytogenes

APC108883
(show subtarget assignments)

1

soluble

213524750

regulatory protein, LacI

338

MCSG::Biology::Human Microbiome

1BDI

27.8%

Bifidobacterium longum

APC110143
(show subtarget assignments)

1

in_crystallization_trials

15615135

stage V sporulation protein [Bacillus ha...

644

MCSG::Biology::Essential Enzymes

3EQU

27.8%

Bacillus halodurans

APC100708
(show subtarget assignments)

1

in_pdb
3R0V

Sthe_2971

269788233

alpha/beta hydrolase fold protein [Sphae...

259

MCSG::Coverage::GEBA

2XUA

27.8%

Sphaerobacter thermophilus

APC105844
(show subtarget assignments)

3

purified

34103893

probable secreted protein EspA [Chromoba...

184

CONS::PCSEP::Effectors

1XOU

27.8%

Chromobacterium violaceum

APC109357
(show subtarget assignments)

7

selected

410025766

KedU21

352

CONS::NATPRO::Enzymes

3O04

27.8%

Streptoalloteichus sp.

APC110247
(show subtarget assignments)

1

expression_tested

27379174

hypothetical protein [Bradyrhizobium jap...

389

MCSG::Coverage::SBP

3H75

27.8%

Bradyrhizobium diazoefficiens

APC107197
(show subtarget assignments)

1

soluble

257168746

metallophosphoesterase [Halomicrobium mu...

187

MCSG::Coverage::GEBA

1XM7

27.8%

Halomicrobium mukohataei

APC106924
(show subtarget assignments)

3

selected

15239263

concanavalin A-like lectin kinase-like p...

288

COMM::UofMissouri::Factors

5AVA

27.8%

Arabidopsis thaliana

APC105973
(show subtarget assignments)

9

soluble

15607533

ndhA gene product [Mycobacterium tubercu...

470

CONS::MTBI::Essential Enzymes

4G6G

27.9%

Mycobacterium tuberculosis

APC100010
(show subtarget assignments)

1

purified

AAur_3119

119961949

glycoside hydrolase family protein [Arth...

465

MCSG::Biology::Human Microbiome

1UYP

27.9%

Arthrobacter aurescens

APC116098
(show subtarget assignments)

1

soluble

1

241

CONS::NATPRO::Enzymes

1YW0

27.9%

root

APC109435
(show subtarget assignments)

7

selected

26541538

LnmL

86

CONS::NATPRO::Enzymes

2DNW

27.9%

Streptomyces atroolivaceus

APC103249
(show subtarget assignments)

1

selected

296021513

phosphopantothenoylcysteine decarboxylas...

416

MCSG::Coverage::GEBA

4QJI

27.9%

Cellulomonas flavigena

APC103241
(show subtarget assignments)

1

selected

296023275

HAD-superfamily hydrolase, subfamily IA,...

214

MCSG::Coverage::GEBA

3E58

27.9%

Cellulomonas flavigena

APC105804
(show subtarget assignments)

9

selected

9951045

conserved hypothetical protein

297

CONS::PCSEP::Effectors

4OTP

27.9%

Pseudomonas aeruginosa

APC109164
(show subtarget assignments)

7

selected

238626064

NosN [Streptomyces actuosus]

395

CONS::NATPRO::Enzymes

1OLT

27.9%

Streptomyces actuosus

APC111225
(show subtarget assignments)

1

purified

170078895

penicillin-binding protein [Synechococcu...

641

MCSG::Biology::Essential Enzymes

3OC2

27.9%

Synechococcus sp.

APC103105
(show subtarget assignments)

1

expression_tested

256558789

acetyltransferase (GNAT) family protein ...

328

MCSG::Coverage::GEBA

3TT2

27.9%

Brachybacterium faecium

APC101100
(show subtarget assignments)

1

crystallized

Dtox_2750

257779634

transcriptional regulator, Crp/Fnr famil...

222

MCSG::Coverage::GEBA

3FWE

27.9%

Desulfotomaculum acetoxidans

APC100302
(show subtarget assignments)

1

in_pdb
4OVJ

Aaci_2460

257479147

extracellular solute-binding protein fam...

441

MCSG::Coverage::GEBA

4R6K

27.9%

Alicyclobacillus acidocaldarius

APC100309
(show subtarget assignments)

1

expression_tested

Aaci_0788

257477512

Carbohydrate kinase, FGGY-like protein [...

441

MCSG::Coverage::GEBA

5VM1

27.9%

Alicyclobacillus acidocaldarius

APC100293
(show subtarget assignments)

1

in_pdb
3RAC

Aaci_0923

257477644

Histidine--tRNA ligase [Alicyclobacillus...

370

MCSG::Coverage::GEBA

3OD1

27.9%

Alicyclobacillus acidocaldarius

APC113667
(show subtarget assignments)

1

expression_tested

0

165

COMM::IASTATE::SoilCAZY

3GM8

27.9%

Mycobacterium sp.

APC100217
(show subtarget assignments)

1

soluble

21218824

alpha-galactosidase SCF8502 [Streptomyce...

499

MCSG::Biology::Human Microbiome

1ZY9

27.9%

Streptomyces coelicolor

APC108915
(show subtarget assignments)

1

soluble

213523024

periplasmic binding protein/LacI transcr...

337

MCSG::Biology::Human Microbiome

3DBI

27.9%

Bifidobacterium longum

APC100668
(show subtarget assignments)

1

expression_tested

Plim_1594

296014188

O-methyltransferase family 2 [Planctomyc...

387

MCSG::Coverage::GEBA

3GWZ

27.9%

Planctomyces limnophilus

APC110657
(show subtarget assignments)

1

purified

256833734

peptidoglycan glycosyltransferase [Jones...

764

MCSG::Biology::Essential Enzymes

4OON

27.9%

Jonesia denitrificans

APC106599
(show subtarget assignments)

1

soluble

0

conserved hypothetical protein

237

MCSG::Biology::Pathogens

4YC5

27.9%

Synechococcus sp.

APC113571
(show subtarget assignments)

1

expression_tested

0

165

COMM::IASTATE::SoilCAZY

3GM8

27.9%

Microbacterium sp.

APC101614
(show subtarget assignments)

9

selected

267994617

putative inner membrane protein [Salmon...

86

CONS::PCSEP::Effectors

4RQW

27.9%

Salmonella enterica

APC108632
(show subtarget assignments)

5

selected

37528063

hypothetical protein plu4227 [Photorhabd...

510

COMM::HARVARD::TypeVI

3J9O

27.9%

Photorhabdus luminescens

APC100760
(show subtarget assignments)

1

in_crystallization_trials

Sthe_1128

269786421

FAD-dependent pyridine nucleotide-disulp...

390

MCSG::Coverage::GEBA

3VRD

27.9%

Sphaerobacter thermophilus

APC107221
(show subtarget assignments)

1

purified

257170960

Electron transfer flavoprotein alpha/bet...

287

MCSG::Coverage::GEBA

4KPU

27.9%

Halomicrobium mukohataei

APC106824
(show subtarget assignments)

7

purified

16802654

hypothetical protein lmo0612 [Listeria m...

151

COMM::IIT::Listeria.TF

3BDD

27.9%

Listeria monocytogenes

APC103671
(show subtarget assignments)

1

crystallized

256587420

transcriptional regulator, RpiR family [...

333

MCSG::Coverage::GEBA

4IVN

27.9%

Saccharomonospora viridis

APC108934
(show subtarget assignments)

1

soluble

255345146

periplasmic binding protein/LacI transcr...

340

MCSG::Biology::Human Microbiome

3CTP

28%

Pedobacter heparinus

APC103637
(show subtarget assignments)

1

soluble

255343019

Thiamine-phosphate diphosphorylase [Pedo...

210

MCSG::Coverage::GEBA

1XI3

28%

Pedobacter heparinus

APC106665
(show subtarget assignments)

1

soluble

60495091

putative 2-oxoglutarate ferredoxin oxido...

616

MCSG::Biology::Pathogens

5B46

28%

Bacteroides fragilis

APC105720
(show subtarget assignments)

0

expression_tested

0

314

CONS::MTBI::Essential Enzymes

4X6G

28%

Mycobacterium tuberculosis

APC115024
(show subtarget assignments)

1

selected

189436857

879

MCSG::Biology::Human Microbiome

5TF0

28%

Bacteroides intestinalis

APC101012
(show subtarget assignments)

1

purified

Aaci_1878

257478571

transcriptional regulator, MarR family [...

158

MCSG::Coverage::GEBA

4NB5

28%

Alicyclobacillus acidocaldarius

APC109137
(show subtarget assignments)

8

expression_tested

28192467

NDP-hexose-4-ketoreductase [Streptomyces...

265

CONS::NATPRO::Enzymes

4TWR

28%

Streptomyces carzinostaticus

APC108607
(show subtarget assignments)

5

selected

206558748

putative type VI secretion system protei...

496

COMM::HARVARD::TypeVI

3J9O

28%

Burkholderia cenocepacia

APC113654
(show subtarget assignments)

1

soluble

0

150

COMM::IASTATE::SoilCAZY

1KWG

28%

Mycobacterium sp.

APC108781
(show subtarget assignments)

1

soluble

213524341

extracellular solute-binding protein, fa...

315

MCSG::Biology::Human Microbiome

4G4P

28%

Bifidobacterium longum

APC113558
(show subtarget assignments)

1

selected

0

150

COMM::IASTATE::SoilCAZY

1KWG

28%

Microbacterium sp.

APC103330
(show subtarget assignments)

1

selected

283947912

amidohydrolase 2 [Conexibacter woesei DS...

300

MCSG::Coverage::GEBA

3IRS

28%

Conexibacter woesei

APC105845
(show subtarget assignments)

3

purified

34103890

probable secreted protein EspA

186

CONS::PCSEP::Effectors

1XOU

28%

Chromobacterium violaceum

APC103091
(show subtarget assignments)

1

purified

229567202

molybdopterin-guanine dinucleotide biosy...

206

MCSG::Coverage::GEBA

1HJJ

28%

Beutenbergia cavernae

APC107274
(show subtarget assignments)

1

purified

257050919

chromosome segregation and condensation ...

207

MCSG::Coverage::GEBA

4I98

28%

Leptotrichia buccalis

APC100765
(show subtarget assignments)

1

expression_tested

Sthe_1744

269787035

peptidase S1 and S6 chymotrypsin/Hap [Sp...

282

MCSG::Coverage::GEBA

1Y8T

28%

Sphaerobacter thermophilus

APC106563
(show subtarget assignments)

1

soluble

0

hypothetical

118

MCSG::Biology::Pathogens

2CWY

28%

Synechococcus sp.

APC107012
(show subtarget assignments)

1

soluble

269785341

glycosyl transferase family 9 [Sphaeroba...

355

MCSG::Coverage::GEBA

3TOV

28%

Sphaerobacter thermophilus

APC111026
(show subtarget assignments)

1

soluble

269793871

transcriptional regulator [Sanguibacter ...

371

MCSG::Coverage::SBP

5UFH

28%

Sanguibacter keddieii

APC109084
(show subtarget assignments)

7

expression_tested

24575108

type II PCP [Streptomyces globisporus]

93

CONS::NATPRO::Enzymes

2MR7

28%

Streptomyces globisporus

APC113279
(show subtarget assignments)

9

soluble

397675289

243

COMM::SDDC

2YQZ

28%

Mycobacterium tuberculosis

APC102527
(show subtarget assignments)

3

in_crystallization_trials

112360078

putative HAD-superfamily hydrolase

212

CONS::PCSEP::Effectors

3FVV

28.1%

Campylobacter jejuni

APC110470
(show subtarget assignments)

1

expression_tested

110636601

glycosyltransferase [Cytophaga hutchinso...

762

MCSG::Biology::Essential Enzymes

3UDF

28.1%

Cytophaga hutchinsonii

APC110573
(show subtarget assignments)

1

expression_tested

238924608

peptidoglycan glycosyltransferase [Eubac...

530

MCSG::Biology::Essential Enzymes

4BJP

28.1%

Eubacterium rectale

APC103535
(show subtarget assignments)

1

soluble

283812872

phosphogluconate dehydrogenase, NAD-bind...

253

MCSG::Coverage::GEBA

5A9R

28.1%

Kribbella flavida

APC108402
(show subtarget assignments)

7

in_crystallization_trials

16262911

NodD3 nod box-dependent transcriptional ...

313

COMM::STANFORD::Nod-box

1UTB

28.1%

Sinorhizobium meliloti

APC100726
(show subtarget assignments)

1

in_pdb
4U4E

SPA3000

269785833

thiolase [Sphaerobacter thermophilus DSM...

383

MCSG::Coverage::GEBA

5AB4

28.1%

Sphaerobacter thermophilus

APC106535
(show subtarget assignments)

1

selected

39650631

pimeloyl-CoA dehydrogenase (small subuni...

380

MCSG::Biology::Pathogens

1BUC

28.1%

Rhodopseudomonas palustris

APC108777
(show subtarget assignments)

1

expression_tested

219536659

Dhaf_0331

542

MCSG::Biology::Human Microbiome

3RY3

28.1%

Desulfitobacterium hafniense

APC107414
(show subtarget assignments)

4

purified

15609352

dihydrolipoamide acetyltransferase [Myco...

553

CONS::MTBI::Essential Enzymes

3DUF

28.1%

Mycobacterium tuberculosis

APC100341
(show subtarget assignments)

1

in_pdb
4DZR

Aaci_2779

257479464

protein-(glutamine-N5) methyltransferase...

313

MCSG::Coverage::GEBA

1NV8

28.1%

Alicyclobacillus acidocaldarius

APC100197
(show subtarget assignments)

1

soluble

SAV_3019

29829561

beta-N-acetylhexosaminidase [Streptomyce...

534

MCSG::Biology::Human Microbiome

3TEV

28.1%

Streptomyces avermitilis

APC113042
(show subtarget assignments)

1

expression_tested

302150446

glycosyl hydrolase family 25

228

MCSG::Biology::Human Microbiome

1JFX

28.1%

Prevotella melaninogenica

APC103688
(show subtarget assignments)

1

expression_tested

269097975

metal-dependent hydrolase, beta-lactamas...

267

MCSG::Coverage::GEBA

1ZKP

28.1%

Sanguibacter keddieii

APC110441
(show subtarget assignments)

1

in_crystallization_trials

283950521

hypothetical protein

246

MCSG::Coverage::BIG-PFAM

3HQV

28.1%

Conexibacter woesei

APC116015
(show subtarget assignments)

9

soluble

0

448

CONS::NATPRO::Enzymes

2BVJ

28.1%

APC103452
(show subtarget assignments)

1

soluble

262078253

Haloacid dehalogenase domain protein hyd...

217

MCSG::Coverage::GEBA

4EX6

28.1%

Haliangium ochraceum

APC105886
(show subtarget assignments)

9

selected

13361541

IpaH-like protein [Escherichia coli O157...

167

CONS::PCSEP::Effectors

1G9U

28.1%

Escherichia coli

APC101195
(show subtarget assignments)

1

soluble

Hmuk_2602

257170949

cytochrome P450 [Halomicrobium mukohatae...

445

MCSG::Coverage::GEBA

5T6Q

28.2%

Halomicrobium mukohataei

APC105971
(show subtarget assignments)

9

purified

15610936

pks13 gene product [Mycobacterium tuberc...

1733

CONS::MTBI::Essential Enzymes

3TZW

28.2%

Mycobacterium tuberculosis

APC113426
(show subtarget assignments)

1

soluble

478765523

273

MCSG::Coverage::FunFam

4JC0

28.2%

Thermoplasmatales archaeon

APC103759
(show subtarget assignments)

1

purified

256792321

universal stress protein UspA-like prote...

147

MCSG::Coverage::GEBA

4WNY

28.2%

Slackia heliotrinireducens

APC109025
(show subtarget assignments)

7

expression_tested

83320235

N-glycosyltransferase

445

CONS::NATPRO::Enzymes

3OTG

28.2%

Actinomadura sp.

APC107158
(show subtarget assignments)

1

soluble

257476811

transcriptional regulator, XRE family [A...

262

MCSG::Coverage::GEBA

1S96

28.2%

Alicyclobacillus acidocaldarius

APC106644
(show subtarget assignments)

1

selected

132662865

coenzyme F420-reducing hydrogenase, delt...

174

MCSG::Biology::Pathogens

2E85

28.2%

Methanococcus maripaludis

APC101352
(show subtarget assignments)

1

soluble

Taci_0355

269099605

response regulator receiver modulated di...

464

MCSG::Coverage::GEBA

1W25

28.2%

Thermanaerovibrio acidaminovorans

APC102432
(show subtarget assignments)

1

expression_tested

85776112

putative circadian clock protein, KaiC

494

MCSG::Biology::Type IV orthologs

4O0M

28.2%

Anaeromyxobacter dehalogenans

APC103602
(show subtarget assignments)

1

expression_tested

258554003

transcriptional regulator, AsnC family [...

156

MCSG::Coverage::GEBA

2W25

28.2%

Nakamurella multipartita

APC108613
(show subtarget assignments)

5

selected

83721364

hypothetical protein BTH_I2963 [Burkhold...

496

COMM::HARVARD::TypeVI

3J9O

28.2%

Burkholderia thailandensis

APC108610
(show subtarget assignments)

5

selected

83716783

unnamed protein product [Burkholderia th...

508

COMM::HARVARD::TypeVI

3J9O

28.2%

Burkholderia thailandensis

APC103322
(show subtarget assignments)

1

selected

283951357

Cytosine deaminase [Conexibacter woesei ...

415

MCSG::Coverage::GEBA

4JNP

28.2%

Conexibacter woesei

APC103075
(show subtarget assignments)

1

purified

229567634

putative regulator [Beutenbergia caverna...

186

MCSG::Coverage::GEBA

3KKD

28.2%

Beutenbergia cavernae

APC107009
(show subtarget assignments)

1

expression_tested

269788007

transcriptional regulator, IclR family [...

270

MCSG::Coverage::GEBA

2G7U

28.2%

Sphaerobacter thermophilus

APC100527
(show subtarget assignments)

1

soluble

Lebu_1620

257050308

oxidoreductase domain protein [Leptotric...

326

MCSG::Coverage::GEBA

3E9M

28.2%

Leptotrichia buccalis

APC109123
(show subtarget assignments)

7

selected

164665143

type II beta-Tyr adenylation domain prot...

1115

CONS::NATPRO::Enzymes

4ZXJ

28.2%

Actinomadura madurae

APC110977
(show subtarget assignments)

1

soluble

99078287

LacI family transcription regulator [Rue...

362

MCSG::Coverage::SBP

3H5O

28.2%

Ruegeria sp.

APC109715
(show subtarget assignments)

7

selected

357415467

Sfla_6318

414

CONS::NATPRO::Enzymes

4K5R

28.2%

Streptomyces pratensis

APC103387
(show subtarget assignments)

1

in_pdb
4GBJ

254950143

6-phosphogluconate dehydrogenase NAD-bin...

294

MCSG::Coverage::GEBA

1YB4

28.2%

Dyadobacter fermentans

APC108801
(show subtarget assignments)

1

soluble

283814563

transcriptional regulator, LysR family

305

MCSG::Biology::Human Microbiome

2H98

28.2%

Spirosoma linguale

APC101194
(show subtarget assignments)

1

purified

Hmuk_2500

257170849

molybdenum cofactor biosynthesis protein...

335

MCSG::Coverage::GEBA

1TV7

28.3%

Halomicrobium mukohataei

APC103023
(show subtarget assignments)

1

selected

255923045

FAD dependent oxidoreductase [Actinosynn...

389

MCSG::Coverage::GEBA

4YSH

28.3%

Actinosynnema mirum

APC108735
(show subtarget assignments)

1

purified

238875128

transcriptional regulator (LacI family)

336

MCSG::Biology::Human Microbiome

1BDI

28.3%

Eubacterium rectale

APC112013
(show subtarget assignments)

9

soluble

15609368

364

CONS::MTBI::Essential Enzymes

1LC5

28.3%

Mycobacterium tuberculosis

APC107492
(show subtarget assignments)

3

soluble

15610645

hypothetical protein Rv3509c [Mycobacter...

515

CONS::MTBI::Essential Enzymes

4MQ5

28.3%

Mycobacterium tuberculosis

APC103556
(show subtarget assignments)

1

purified

283807802

Acyl-CoA synthetase (AMP-forming)/AMP-ac...

418

MCSG::Coverage::GEBA

4GR5

28.3%

Kribbella flavida

APC103543
(show subtarget assignments)

1

crystallized

283810767

modification methylase, HemK family [Kri...

262

MCSG::Coverage::GEBA

1NV8

28.3%

Kribbella flavida

APC103237
(show subtarget assignments)

1

expression_tested

296021138

Ribonuclease H [Cellulomonas flavigena D...

279

MCSG::Coverage::GEBA

2ETJ

28.3%

Cellulomonas flavigena

APC103360
(show subtarget assignments)

1

expression_tested

257798550

type IV pilus assembly protein PilM [Des...

325

MCSG::Coverage::GEBA

2YCH

28.3%

Desulfohalobium retbaense

APC103168
(show subtarget assignments)

1

expression_tested

256361643

acyl-CoA dehydrogenase domain protein [C...

381

MCSG::Coverage::GEBA

4M9A

28.3%

Catenulispora acidiphila

APC104209
(show subtarget assignments)

1

soluble

257055429

CRISPR-associated protein, Cse4 family

368

MCSG::Technology::Complexes

1VY8

28.3%

Saccharomonospora viridis

APC100343
(show subtarget assignments)

1

soluble

Aaci_0075

257476820

extracellular solute-binding protein fam...

441

MCSG::Coverage::GEBA

4QRZ

28.3%

Alicyclobacillus acidocaldarius

APC100328
(show subtarget assignments)

1

purified

Aaci_0913

257477634

extracellular solute-binding protein fam...

421

MCSG::Coverage::GEBA

4R9F

28.3%

Alicyclobacillus acidocaldarius

APC100477
(show subtarget assignments)

1

in_crystallization_trials

Dtox_1281

257778269

oxidoreductase FAD/NAD(P)-binding domain...

279

MCSG::Coverage::GEBA

4YLF

28.3%

Desulfotomaculum acetoxidans

APC102426
(show subtarget assignments)

1

expression_tested

85775448

Methyltransferase type 11

222

MCSG::Biology::Type IV orthologs

4C03

28.3%

Anaeromyxobacter dehalogenans

APC106624
(show subtarget assignments)

1

soluble

33566762

putative ring-hydroxylating dioxygenase ...

173

MCSG::Biology::Pathogens

3EN1

28.3%

Bordetella parapertussis

APC100413
(show subtarget assignments)

1

expression_tested

Dtox_3253

257780094

type IV pilus assembly protein PilM [Des...

350

MCSG::Coverage::GEBA

2YCH

28.3%

Desulfotomaculum acetoxidans

APC108861
(show subtarget assignments)

1

soluble

150955138

putative transcriptional regulator (LysR...

301

MCSG::Biology::Human Microbiome

3HHG

28.3%

Klebsiella pneumoniae

APC109179
(show subtarget assignments)

7

expression_tested

119433779

TlmVII [Streptoalloteichus hindustanus]

1141

CONS::NATPRO::Enzymes

4ZXJ

28.3%

Streptoalloteichus hindustanus

APC108745
(show subtarget assignments)

1

expression_tested

150955219

putative transcriptional regulator (LysR...

310

MCSG::Biology::Human Microbiome

3SZP

28.3%

Klebsiella pneumoniae

APC108737
(show subtarget assignments)

1

soluble

150955139

putative transcriptional regulator (LysR...

300

MCSG::Biology::Human Microbiome

3T1B

28.3%

Klebsiella pneumoniae

APC100823
(show subtarget assignments)

1

crystallized

Vpar_0360

269094053

beta-lactamase domain protein [Veillonel...

411

MCSG::Coverage::GEBA

1YCF

28.3%

Veillonella parvula

APC108888
(show subtarget assignments)

1

selected

125715215

transcriptional regulator, LacI family

342

MCSG::Biology::Human Microbiome

1RZR

28.3%

Ruminiclostridium thermocellum

APC107089
(show subtarget assignments)

1

soluble

257048783

Glutamyl-tRNA reductase [Leptotrichia bu...

346

MCSG::Coverage::GEBA

1GPJ

28.3%

Leptotrichia buccalis

APC111070
(show subtarget assignments)

1

soluble

269929012

Extracellular ligand-binding receptor [S...

375

MCSG::Coverage::SBP

3IP5

28.3%

Sphaerobacter thermophilus

Targets