|
|---|
| MCSG ID |
Priority |
stage |
Locus Tag |
NCBI GI |
Gene
Name |
Common Name |
Sequence
Length |
Project |
Homolog
PDB ID |
Homolog
Sequence
Identity |
Target Organism |
Request Person |
APC105857
(show subtarget assignments)
|
3
|
expression_tested
|
|
13361024
|
|
putative secreted effector protein |
782 |
CONS::PCSEP::Effectors |
3NAW
|
78.4% |
Escherichia coli |
|
|
|
APC105856
(show subtarget assignments)
|
3
|
soluble
|
|
13364031
|
|
EspA protein |
192 |
CONS::PCSEP::Effectors |
1XOU
|
80.7% |
Escherichia coli |
|
|
|
APC105855
(show subtarget assignments)
|
3
|
purified
|
|
34103575
|
|
hypothetical protein |
298 |
CONS::PCSEP::Effectors |
|
|
Chromobacterium violaceum |
|
|
|
APC105854
(show subtarget assignments)
|
3
|
expression_tested
|
|
34103741
|
|
conserved hypothetical protein |
366 |
CONS::PCSEP::Effectors |
4BVU
|
11.5% |
Chromobacterium violaceum |
|
|
|
APC105853
(show subtarget assignments)
|
3
|
expression_tested
|
|
34103887
|
|
secretion system effector |
495 |
CONS::PCSEP::Effectors |
5GAO
|
13.1% |
Chromobacterium violaceum |
|
|
|
APC105852
(show subtarget assignments)
|
3
|
expression_tested
|
|
34102306
|
|
lipase/esterase |
712 |
CONS::PCSEP::Effectors |
3KVN
|
23.9% |
Chromobacterium violaceum |
|
|
|
APC105851
(show subtarget assignments)
|
3
|
purified
|
|
34103603
|
|
hypothetical protein |
421 |
CONS::PCSEP::Effectors |
5CQ9
|
8.8% |
Chromobacterium violaceum |
|
|
|
APC105850
(show subtarget assignments)
|
3
|
purified
|
|
34103892
|
|
probable secreted protein EspA |
262 |
CONS::PCSEP::Effectors |
|
|
Chromobacterium violaceum |
|
|
|
APC105849
(show subtarget assignments)
|
3
|
purified
|
|
34103889
|
|
probable secreted protein EspA |
285 |
CONS::PCSEP::Effectors |
|
|
Chromobacterium violaceum |
|
|
|
APC105848
(show subtarget assignments)
|
3
|
soluble
|
|
34330264
|
|
probable thermolabile hemolysin [Chromob... |
417 |
CONS::PCSEP::Effectors |
|
|
Chromobacterium violaceum |
|
|
|
APC105847
(show subtarget assignments)
|
3
|
soluble
|
|
34330265
|
|
probable thermolabile hemolysin, lecithi... |
404 |
CONS::PCSEP::Effectors |
3KVN
|
16.8% |
Chromobacterium violaceum |
|
|
|
APC105846
(show subtarget assignments)
|
3
|
soluble
|
|
34332841
|
|
cell invasion protein |
355 |
CONS::PCSEP::Effectors |
|
|
Chromobacterium violaceum |
|
|
|
APC105845
(show subtarget assignments)
|
3
|
purified
|
|
34103890
|
|
probable secreted protein EspA |
186 |
CONS::PCSEP::Effectors |
1XOU
|
28% |
Chromobacterium violaceum |
|
|
|
APC105844
(show subtarget assignments)
|
3
|
purified
|
|
34103893
|
|
probable secreted protein EspA [Chromoba... |
184 |
CONS::PCSEP::Effectors |
1XOU
|
27.8% |
Chromobacterium violaceum |
|
|
|
APC105843
(show subtarget assignments)
|
3
|
soluble
|
|
34105155
|
|
probable serine/threonine kinase |
298 |
CONS::PCSEP::Effectors |
5HNV
|
31.2% |
Chromobacterium violaceum |
|
|
|
APC105842
(show subtarget assignments)
|
3
|
soluble
|
|
34332794
|
|
probable SPI2 translocated effector [Chr... |
337 |
CONS::PCSEP::Effectors |
4QXM
|
8.3% |
Chromobacterium violaceum |
|
|
|
APC105841
(show subtarget assignments)
|
3
|
expression_tested
|
|
34103929
|
|
cell invasion protein |
583 |
CONS::PCSEP::Effectors |
3TUL
|
13% |
Chromobacterium violaceum |
|
|
|
APC105840
(show subtarget assignments)
|
3
|
soluble
|
|
83651346
|
|
conserved hypothetical protein |
716 |
CONS::PCSEP::Effectors |
|
|
Burkholderia thailandensis |
|
|
|
APC105839
(show subtarget assignments)
|
3
|
soluble
|
|
83651991
|
|
type III secretion target BipC |
409 |
CONS::PCSEP::Effectors |
|
|
Burkholderia thailandensis |
|
|
|
APC105838
(show subtarget assignments)
|
3
|
purified
|
|
83653562
|
|
conserved hypothetical protein |
379 |
CONS::PCSEP::Effectors |
3KVN
|
25% |
Burkholderia thailandensis |
|
|
|
APC105837
(show subtarget assignments)
|
3
|
soluble
|
|
83650686
|
|
serine/threonine protein kinase |
877 |
CONS::PCSEP::Effectors |
5HNV
|
16.6% |
Burkholderia thailandensis |
|
|
|
APC105836
(show subtarget assignments)
|
3
|
expression_tested
|
|
83650527
|
|
pentapeptide repeat family protein |
356 |
CONS::PCSEP::Effectors |
4YFO
|
14.9% |
Burkholderia thailandensis |
|
|
|
APC105835
(show subtarget assignments)
|
3
|
soluble
|
|
83650903
|
|
BipB protein |
624 |
CONS::PCSEP::Effectors |
5GAO
|
12.7% |
Burkholderia thailandensis |
|
|
|
APC105834
(show subtarget assignments)
|
3
|
expression_tested
|
|
33573533
|
|
putative outer protein B |
402 |
CONS::PCSEP::Effectors |
5GAO
|
14.4% |
Bordetella parapertussis |
|
|
|
APC105833
(show subtarget assignments)
|
3
|
purified
|
|
33565505
|
|
hypothetical protein |
400 |
CONS::PCSEP::Effectors |
5GAO
|
19% |
Bordetella parapertussis |
|
|
|
APC105832
(show subtarget assignments)
|
3
|
expression_tested
|
|
33575056
|
|
putative membrane protein |
410 |
CONS::PCSEP::Effectors |
5HNV
|
15.6% |
Bordetella bronchiseptica |
|
|
|
APC105831
(show subtarget assignments)
|
3
|
soluble
|
|
33576830
|
|
conserved hypothetical protein |
244 |
CONS::PCSEP::Effectors |
|
|
Bordetella bronchiseptica |
|
|
|
APC105830
(show subtarget assignments)
|
3
|
expression_tested
|
|
33567382
|
|
conserved hypothetical protein |
353 |
CONS::PCSEP::Effectors |
4YFO
|
21.2% |
Bordetella bronchiseptica |
|
|
|
APC105829
(show subtarget assignments)
|
9
|
selected
|
|
78034457
|
|
avirulence protein AvrRxv |
373 |
CONS::PCSEP::Effectors |
5KLQ
|
24.6% |
Xanthomonas campestris |
|
|
|
APC105828
(show subtarget assignments)
|
9
|
selected
|
|
78036142
|
|
Xanthomonas outer protein J |
373 |
CONS::PCSEP::Effectors |
5KLQ
|
25.5% |
Xanthomonas campestris |
|
|
|
APC105827
(show subtarget assignments)
|
9
|
crystallized
|
|
78037206
|
|
conserved hypothetical protein |
660 |
CONS::PCSEP::Effectors |
4FCG
|
46.5% |
Xanthomonas campestris |
|
|
|
APC105826
(show subtarget assignments)
|
9
|
in_crystallization_trials
|
|
21115468
|
|
leucin rich protein |
504 |
CONS::PCSEP::Effectors |
4FCG
|
30.7% |
Xanthomonas campestris |
|
|
|
APC105825
(show subtarget assignments)
|
9
|
selected
|
|
18462542
|
|
OspG, secreted by the Mxi-Spa secretion ... |
196 |
CONS::PCSEP::Effectors |
4BVU
|
100% |
Shigella flexneri |
|
|
|
APC105824
(show subtarget assignments)
|
9
|
selected
|
|
24052093
|
|
putative glycoprotein |
329 |
CONS::PCSEP::Effectors |
1O6S
|
26.4% |
Shigella flexneri |
|
|
|
APC105823
(show subtarget assignments)
|
9
|
selected
|
|
24051478
|
|
invasion plasmid antigen |
347 |
CONS::PCSEP::Effectors |
4U08
|
27% |
Shigella flexneri |
|
|
|
APC105822
(show subtarget assignments)
|
9
|
selected
|
|
24052092
|
|
orf, conserved hypothetical protein |
161 |
CONS::PCSEP::Effectors |
1G9U
|
29.1% |
Shigella flexneri |
|
|
|
APC105821
(show subtarget assignments)
|
9
|
selected
|
|
56383690
|
|
invasion plasmid antigen |
608 |
CONS::PCSEP::Effectors |
3CVR
|
64.5% |
Shigella flexneri |
|
|
|
APC105820
(show subtarget assignments)
|
9
|
selected
|
|
24050975
|
|
invasion plasmid antigen |
587 |
CONS::PCSEP::Effectors |
3CVR
|
71.6% |
Shigella flexneri |
|
|
|
APC105819
(show subtarget assignments)
|
9
|
in_crystallization_trials
|
|
18462575
|
|
invasion plasmid antigen, probably secre... |
574 |
CONS::PCSEP::Effectors |
3CVR
|
70.5% |
Shigella flexneri |
|
|
|
APC105818
(show subtarget assignments)
|
9
|
selected
|
|
24052216
|
|
invasion plasmid antigen |
583 |
CONS::PCSEP::Effectors |
3CVR
|
72.8% |
Shigella flexneri |
|
|
|
APC105817
(show subtarget assignments)
|
9
|
in_crystallization_trials
|
|
56383109
|
|
invasion plasmid antigen, secreted by th... |
545 |
CONS::PCSEP::Effectors |
3CVR
|
79.4% |
Shigella flexneri |
|
|
|
APC105816
(show subtarget assignments)
|
9
|
crystallized
|
|
56383112
|
|
invasion plasmid antigen, secreted by th... |
575 |
CONS::PCSEP::Effectors |
3CVR
|
68.9% |
Shigella flexneri |
|
|
|
APC105815
(show subtarget assignments)
|
9
|
in_crystallization_trials
|
|
18462574
|
|
invasion plasmid antigen, probably secre... |
565 |
CONS::PCSEP::Effectors |
3CVR
|
73.1% |
Shigella flexneri |
|
|
|
APC105814
(show subtarget assignments)
|
9
|
purified
|
|
16420597
|
|
secreted effector protein of Salmonella |
782 |
CONS::PCSEP::Effectors |
2QYU
|
79.3% |
Salmonella enterica |
|
|
|
APC105813
(show subtarget assignments)
|
9
|
in_crystallization_trials
|
|
16420779
|
|
Leucine-rich repeat protein |
788 |
CONS::PCSEP::Effectors |
3G06
|
78.6% |
Salmonella enterica |
|
|
|
APC105812
(show subtarget assignments)
|
9
|
selected
|
|
28851432
|
|
pentapeptide repeat domain protein |
114 |
CONS::PCSEP::Effectors |
5DZB
|
18.4% |
Pseudomonas syringae |
|
|
|
APC105811
(show subtarget assignments)
|
9
|
selected
|
|
63255179
|
|
type III effector HopZ3 |
411 |
CONS::PCSEP::Effectors |
5KLQ
|
19.7% |
Pseudomonas syringae |
|
|
|
APC105810
(show subtarget assignments)
|
9
|
selected
|
|
9951199
|
|
hypothetical protein |
307 |
CONS::PCSEP::Effectors |
3KVN
|
27.6% |
Pseudomonas aeruginosa |
|
|
|
APC105809
(show subtarget assignments)
|
9
|
selected
|
|
9950960
|
|
hypothetical protein |
115 |
CONS::PCSEP::Effectors |
5DQA
|
17.4% |
Pseudomonas aeruginosa |
|
|
|
APC105808
(show subtarget assignments)
|
9
|
selected
|
|
9947981
|
|
hypothetical protein |
215 |
CONS::PCSEP::Effectors |
3DU1
|
37.2% |
Pseudomonas aeruginosa |
|
|
|
APC105807
(show subtarget assignments)
|
9
|
selected
|
|
9948510
|
|
hypothetical protein |
159 |
CONS::PCSEP::Effectors |
4YFO
|
30.8% |
Pseudomonas aeruginosa |
|
|
|
APC105806
(show subtarget assignments)
|
9
|
selected
|
|
9951294
|
|
hypothetical protein |
244 |
CONS::PCSEP::Effectors |
|
|
Pseudomonas aeruginosa |
|
|
|
APC105805
(show subtarget assignments)
|
9
|
selected
|
|
9947642
|
|
serine-threonine kinase Stk1 |
329 |
CONS::PCSEP::Effectors |
2W4O
|
28.9% |
Pseudomonas aeruginosa |
|
|
|
APC105804
(show subtarget assignments)
|
9
|
selected
|
|
9951045
|
|
conserved hypothetical protein |
297 |
CONS::PCSEP::Effectors |
4OTP
|
27.9% |
Pseudomonas aeruginosa |
|
|
|
APC105803
(show subtarget assignments)
|
9
|
selected
|
|
9948555
|
|
hypothetical protein PA2502 [Pseudomonas... |
499 |
CONS::PCSEP::Effectors |
4KT1
|
17% |
Pseudomonas aeruginosa |
|
|
|
APC105802
(show subtarget assignments)
|
9
|
selected
|
|
34103574
|
|
conserved hypothetical protein |
60 |
CONS::PCSEP::Effectors |
|
|
Chromobacterium violaceum |
|
|
|
APC105801
(show subtarget assignments)
|
9
|
selected
|
|
34103585
|
|
conserved hypothetical protein |
370 |
CONS::PCSEP::Effectors |
4PED
|
5.9% |
Chromobacterium violaceum |
|
|
|
APC105779
(show subtarget assignments)
|
0
|
purified
|
|
0
|
|
|
297 |
CONS::MTBI::Essential Enzymes |
3FZV
|
28.6% |
Pseudomonas aeruginosa |
|
|
|
APC105778
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
299 |
CONS::MTBI::Essential Enzymes |
|
|
Mycobacterium tuberculosis |
|
|
|
APC105777
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
181 |
CONS::MTBI::Essential Enzymes |
1RTV
|
100% |
Pseudomonas aeruginosa |
|
|
|
APC105776
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
163 |
CONS::MTBI::Essential Enzymes |
5DIR
|
28.8% |
Staphylococcus aureus |
|
|
|
APC105775
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
486 |
CONS::MTBI::Essential Enzymes |
1E0D
|
31.1% |
Mycobacterium tuberculosis |
|
|
|
APC105774
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
169 |
CONS::MTBI::Essential Enzymes |
5DIR
|
100% |
Pseudomonas aeruginosa |
|
|
|
APC105773
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
202 |
CONS::MTBI::Essential Enzymes |
1PM7
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105772
(show subtarget assignments)
|
7
|
purified
|
|
0
|
|
|
794 |
CONS::MTBI::Essential Enzymes |
2OWO
|
48.9% |
Pseudomonas aeruginosa |
|
|
|
APC105771
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
491 |
CONS::MTBI::Essential Enzymes |
4AOS
|
35.5% |
Pseudomonas aeruginosa |
|
|
|
APC105770
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
421 |
CONS::MTBI::Essential Enzymes |
3SG1
|
64.1% |
Staphylococcus aureus |
|
|
|
APC105769
(show subtarget assignments)
|
8
|
soluble
|
|
0
|
|
|
278 |
CONS::MTBI::Essential Enzymes |
3TSM
|
47.1% |
Pseudomonas aeruginosa |
|
|
|
APC105768
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
468 |
CONS::MTBI::Essential Enzymes |
5KCK
|
36.3% |
Staphylococcus aureus |
|
|
|
APC105767
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
487 |
CONS::MTBI::Essential Enzymes |
1E8C
|
47.8% |
Pseudomonas aeruginosa |
|
|
|
APC105766
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
268 |
CONS::MTBI::Essential Enzymes |
5KS2
|
78.4% |
Mycobacterium tuberculosis |
|
|
|
APC105765
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
201 |
CONS::MTBI::Essential Enzymes |
1VS5
|
47.1% |
Mycobacterium tuberculosis |
|
|
|
APC105764
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
421 |
CONS::MTBI::Essential Enzymes |
5BQ2
|
99.8% |
Pseudomonas aeruginosa |
|
|
|
APC105763
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
399 |
CONS::MTBI::Essential Enzymes |
1V0J
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105762
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
222 |
CONS::PCSEP::Effectors |
4IV8
|
23.9% |
Staphylococcus aureus |
|
|
|
APC105761
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
263 |
CONS::MTBI::Essential Enzymes |
3QJ7
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105760
(show subtarget assignments)
|
7
|
in_crystallization_trials
|
|
0
|
|
|
283 |
CONS::MTBI::Essential Enzymes |
1AJ0
|
56.6% |
Pseudomonas aeruginosa |
|
|
|
APC105759
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
492 |
CONS::MTBI::Essential Enzymes |
4PEN
|
46.8% |
Pseudomonas aeruginosa |
|
|
|
APC105758
(show subtarget assignments)
|
8
|
in_crystallization_trials
|
|
0
|
|
|
264 |
CONS::MTBI::Essential Enzymes |
3IX6
|
79.2% |
Pseudomonas aeruginosa |
|
|
|
APC105757
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
269 |
CONS::MTBI::Essential Enzymes |
1P44
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105756
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
418 |
CONS::MTBI::Essential Enzymes |
3R38
|
48.1% |
Mycobacterium tuberculosis |
|
|
|
APC105755
(show subtarget assignments)
|
8
|
in_crystallization_trials
|
|
0
|
|
|
448 |
CONS::MTBI::Essential Enzymes |
1E0D
|
50.6% |
Pseudomonas aeruginosa |
|
|
|
APC105754
(show subtarget assignments)
|
0
|
purified
|
|
0
|
|
|
295 |
CONS::MTBI::Essential Enzymes |
3FZV
|
24.3% |
Staphylococcus aureus |
|
|
|
APC105753
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
206 |
CONS::MTBI::Essential Enzymes |
1VS5
|
74.8% |
Pseudomonas aeruginosa |
|
|
|
APC105752
(show subtarget assignments)
|
8
|
in_pdb
4DQ1
|
|
0
|
|
|
318 |
CONS::MTBI::Essential Enzymes |
3UWL
|
65.4% |
Staphylococcus aureus |
|
|
|
APC105751
(show subtarget assignments)
|
7
|
purified
|
|
0
|
|
|
417 |
CONS::MTBI::Essential Enzymes |
3WQT
|
25.9% |
Pseudomonas aeruginosa |
|
|
|
APC105750
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
265 |
CONS::MTBI::Essential Enzymes |
4NQZ
|
100% |
Pseudomonas aeruginosa |
|
|
|
APC105749
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
458 |
CONS::MTBI::Essential Enzymes |
4CVK
|
99.6% |
Pseudomonas aeruginosa |
|
|
|
APC105748
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
360 |
CONS::MTBI::Essential Enzymes |
4J72
|
48.5% |
Pseudomonas aeruginosa |
|
|
|
APC105747
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
321 |
CONS::MTBI::Essential Enzymes |
5JNQ
|
46.5% |
Staphylococcus aureus |
|
|
|
APC105746
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
677 |
CONS::MTBI::Essential Enzymes |
1F4L
|
52.3% |
Pseudomonas aeruginosa |
|
|
|
APC105745
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
667 |
CONS::MTBI::Essential Enzymes |
3JSL
|
46.6% |
Staphylococcus aureus |
|
|
|
APC105744
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
495 |
CONS::MTBI::Essential Enzymes |
4O5H
|
61.2% |
Pseudomonas aeruginosa |
|
|
|
APC105743
(show subtarget assignments)
|
7
|
purified
|
|
0
|
|
|
460 |
CONS::MTBI::Essential Enzymes |
1LI5
|
59.2% |
Pseudomonas aeruginosa |
|
|
|
APC105742
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
105 |
CONS::MTBI::Essential Enzymes |
3HX9
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105741
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
359 |
CONS::MTBI::Essential Enzymes |
5JNQ
|
36.2% |
Mycobacterium tuberculosis |
|
|
|
APC105740
(show subtarget assignments)
|
8
|
in_pdb
3TY7
|
|
0
|
|
|
475 |
CONS::MTBI::Essential Enzymes |
3B4W
|
42.5% |
Staphylococcus aureus |
|
|
|
APC105739
(show subtarget assignments)
|
8
|
in_pdb
4HB7
|
|
0
|
|
|
267 |
CONS::MTBI::Essential Enzymes |
1AD1
|
95.8% |
Staphylococcus aureus |
|
|
|
APC105738
(show subtarget assignments)
|
7
|
in_crystallization_trials
|
|
0
|
|
|
206 |
CONS::MTBI::Essential Enzymes |
2MLM
|
71.4% |
Staphylococcus aureus |
|
|
|
APC105737
(show subtarget assignments)
|
7
|
purified
|
|
0
|
|
|
476 |
CONS::MTBI::Essential Enzymes |
3TQO
|
44.5% |
Staphylococcus aureus |
|
|
|
APC105736
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
303 |
CONS::MTBI::Essential Enzymes |
5UPG
|
100% |
Pseudomonas aeruginosa |
|
|
|
APC105735
(show subtarget assignments)
|
7
|
purified
|
|
0
|
|
|
466 |
CONS::MTBI::Essential Enzymes |
3I6D
|
47% |
Staphylococcus aureus |
|
|
|
APC105734
(show subtarget assignments)
|
8
|
in_pdb
4FB7
|
|
0
|
|
|
272 |
CONS::MTBI::Essential Enzymes |
3QJA
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105733
(show subtarget assignments)
|
7
|
in_crystallization_trials
|
|
0
|
|
|
569 |
CONS::MTBI::Essential Enzymes |
3LJP
|
32.7% |
Staphylococcus aureus |
|
|
|
APC105732
(show subtarget assignments)
|
8
|
in_pdb
4GMD
4EDH
4E5U
4ESH
|
|
0
|
|
|
210 |
CONS::MTBI::Essential Enzymes |
3UWK
|
100% |
Pseudomonas aeruginosa |
|
|
|
APC105731
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
452 |
CONS::MTBI::Essential Enzymes |
2AM1
|
33.4% |
Staphylococcus aureus |
|
|
|
APC105730
(show subtarget assignments)
|
7
|
in_crystallization_trials
|
|
0
|
|
|
200 |
CONS::MTBI::Essential Enzymes |
1C05
|
58.5% |
Staphylococcus aureus |
|
|
|
APC105729
(show subtarget assignments)
|
0
|
soluble
|
|
0
|
|
|
489 |
CONS::MTBI::Essential Enzymes |
1W4X
|
26.4% |
Mycobacterium tuberculosis |
|
|
|
APC105728
(show subtarget assignments)
|
0
|
expression_tested
|
|
0
|
|
|
393 |
CONS::MTBI::Essential Enzymes |
1X9Y
|
88.8% |
Staphylococcus aureus |
|
|
|
APC105727
(show subtarget assignments)
|
8
|
in_crystallization_trials
|
|
0
|
|
|
657 |
CONS::MTBI::Essential Enzymes |
4QRD
|
79.1% |
Staphylococcus aureus |
|
|
|
APC105726
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
414 |
CONS::MTBI::Essential Enzymes |
3C8Z
|
79% |
Mycobacterium tuberculosis |
|
|
|
APC105725
(show subtarget assignments)
|
5
|
in_pdb
4RTF
|
|
0
|
|
|
625 |
CONS::MTBI::Essential Enzymes |
2V7Y
|
54.4% |
Mycobacterium tuberculosis |
|
|
|
APC105724
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
499 |
CONS::MTBI::Essential Enzymes |
4AOS
|
26.4% |
Pseudomonas aeruginosa |
|
|
|
APC105723
(show subtarget assignments)
|
7
|
crystallized
|
|
0
|
|
|
470 |
CONS::MTBI::Essential Enzymes |
3WQT
|
99.4% |
Staphylococcus aureus |
|
|
|
APC105722
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
489 |
CONS::MTBI::Essential Enzymes |
3B4W
|
39.9% |
Mycobacterium tuberculosis |
|
|
|
APC105721
(show subtarget assignments)
|
8
|
in_crystallization_trials
|
|
0
|
|
|
449 |
CONS::MTBI::Essential Enzymes |
3LK7
|
46.3% |
Staphylococcus aureus |
|
|
|
APC105720
(show subtarget assignments)
|
0
|
expression_tested
|
|
0
|
|
|
314 |
CONS::MTBI::Essential Enzymes |
4X6G
|
28% |
Mycobacterium tuberculosis |
|
|
|
APC105719
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
510 |
CONS::MTBI::Essential Enzymes |
4CVK
|
35% |
Mycobacterium tuberculosis |
|
|
|
APC105718
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
274 |
CONS::PCSEP::Effectors |
2YQZ
|
26.6% |
Pseudomonas aeruginosa |
|
|
|
APC105717
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
691 |
CONS::MTBI::Essential Enzymes |
3SGI
|
87.6% |
Mycobacterium tuberculosis |
|
|
|
APC105716
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
494 |
CONS::MTBI::Essential Enzymes |
4C12
|
99.6% |
Staphylococcus aureus |
|
|
|
APC105715
(show subtarget assignments)
|
8
|
in_crystallization_trials
|
|
0
|
|
|
108 |
CONS::MTBI::Essential Enzymes |
1SQE
|
100% |
Staphylococcus aureus |
|
|
|
APC105714
(show subtarget assignments)
|
3
|
expression_tested
|
|
0
|
|
|
280 |
CONS::MTBI::Essential Enzymes |
1EYE
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105713
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
256 |
CONS::MTBI::Essential Enzymes |
3GNS
|
100% |
Staphylococcus aureus |
|
|
|
APC105712
(show subtarget assignments)
|
2
|
in_crystallization_trials
|
|
0
|
|
|
301 |
CONS::MTBI::Essential Enzymes |
2FK7
|
99% |
Mycobacterium tuberculosis |
|
|
|
APC105711
(show subtarget assignments)
|
7
|
in_crystallization_trials
|
|
0
|
|
|
394 |
CONS::MTBI::Essential Enzymes |
1KP9
|
27.4% |
Pseudomonas aeruginosa |
|
|
|
APC105710
(show subtarget assignments)
|
8
|
crystallized
|
|
0
|
|
|
450 |
CONS::MTBI::Essential Enzymes |
3RV8
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105709
(show subtarget assignments)
|
0
|
expression_tested
|
|
0
|
|
|
201 |
CONS::MTBI::Essential Enzymes |
1RO5
|
98% |
Pseudomonas aeruginosa |
|
|
|
APC105708
(show subtarget assignments)
|
8
|
soluble
|
|
0
|
|
|
260 |
CONS::MTBI::Essential Enzymes |
1PII
|
34.6% |
Staphylococcus aureus |
|
|
|
APC105707
(show subtarget assignments)
|
7
|
soluble
|
|
0
|
|
|
228 |
CONS::MTBI::Essential Enzymes |
1VS5
|
73.3% |
Pseudomonas aeruginosa |
|
|
|
APC105706
(show subtarget assignments)
|
7
|
expression_tested
|
|
0
|
|
|
202 |
CONS::MTBI::Essential Enzymes |
5DIR
|
29.2% |
Mycobacterium tuberculosis |
|
|
|
APC105705
(show subtarget assignments)
|
7
|
in_pdb
4S1W
|
|
0
|
|
|
601 |
CONS::MTBI::Essential Enzymes |
4AMV
|
41.5% |
Staphylococcus aureus |
|
|
|
APC105704
(show subtarget assignments)
|
8
|
in_pdb
4DWJ
4EAQ
4F4I
4MQB
|
|
0
|
|
|
205 |
CONS::MTBI::Essential Enzymes |
2CCG
|
100% |
Staphylococcus aureus |
|
|
|
APC105703
(show subtarget assignments)
|
4
|
soluble
|
|
0
|
|
|
519 |
CONS::MTBI::Essential Enzymes |
2X1L
|
74.3% |
Mycobacterium tuberculosis |
|
|
|
APC105702
(show subtarget assignments)
|
7
|
in_crystallization_trials
|
|
0
|
|
|
535 |
CONS::MTBI::Essential Enzymes |
2WTZ
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105701
(show subtarget assignments)
|
8
|
purified
|
|
0
|
|
|
214 |
CONS::MTBI::Essential Enzymes |
1G3U
|
100% |
Mycobacterium tuberculosis |
|
|
|
APC105593
(show subtarget assignments)
|
1
|
selected
|
|
15677275
|
|
|
867 |
MCSG::Biology::Essential Enzymes |
2GTQ
|
100% |
Neisseria meningitidis |
|
|
|
APC105592
(show subtarget assignments)
|
1
|
in_pdb
4RGU
4RGX
4RGR
4RGS
|
|
50084882
|
|
transcriptional regulator [Acinetobacter... |
159 |
MCSG::Biology::Essential Enzymes |
3K0L
|
100% |
Acinetobacter sp. |
|
|
|
APC105591
(show subtarget assignments)
|
1
|
in_pdb
4LLE
4LLC
|
|
15600677
|
|
two-component sensor [Pseudomonas aerugi... |
595 |
MCSG::Biology::Essential Enzymes |
3KKB
|
21.5% |
Pseudomonas aeruginosa |
|
|
|
APC105590
(show subtarget assignments)
|
3
|
expressed
|
lpg2720 |
52630036
|
|
cNMP binding domain-containing protein |
343 |
CONS::PCSEP::Effectors |
1RUO
|
13.7% |
Legionella pneumophila |
|
|
|
APC105589
(show subtarget assignments)
|
3
|
selected
|
lpg2346 |
52629667
|
|
transcriptional regulator |
312 |
CONS::PCSEP::Effectors |
2QV7
|
28.8% |
Legionella pneumophila |
|
|
|
APC105588
(show subtarget assignments)
|
3
|
purified
|
lpg0103 |
52627469
|
|
N-terminal acetyltransferase, GNAT famil... |
286 |
CONS::PCSEP::Effectors |
4MBU
|
10.1% |
Legionella pneumophila |
|
|
|
APC105587
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg2482 |
52629801
|
|
SdbC |
448 |
CONS::PCSEP::Effectors |
3TRD
|
9.6% |
Legionella pneumophila |
|
|
|
APC105586
(show subtarget assignments)
|
3
|
in_pdb
4KSN
|
lpg2391 |
52629711
|
|
SdbC |
434 |
COMM::UT::Legionella Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105585
(show subtarget assignments)
|
3
|
crystallized
|
lpg1642 |
52628981
|
|
SidB |
417 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105584
(show subtarget assignments)
|
3
|
in_pdb
4QN8
|
lpg2813 |
52630120
|
|
VipE |
286 |
COMM::UT::Legionella Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105583
(show subtarget assignments)
|
3
|
purified
|
lpg2525 |
52629844
|
|
hypothetical protein |
444 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105582
(show subtarget assignments)
|
3
|
purified
|
lpg2224 |
52629548
|
|
UVB-resistance protein UVR8 |
593 |
CONS::PCSEP::Effectors |
4NAA
|
18.2% |
Legionella pneumophila |
|
|
|
APC105581
(show subtarget assignments)
|
3
|
soluble
|
lpg2144 |
52629469
|
|
F-box protein |
172 |
CONS::PCSEP::Effectors |
5K35
|
97.7% |
Legionella pneumophila |
|
|
|
APC105580
(show subtarget assignments)
|
3
|
purified
|
lpg2137 |
52629462
|
|
calmodulin-dependent protein kinase |
538 |
CONS::PCSEP::Effectors |
5EZR
|
8.9% |
Legionella pneumophila |
|
|
|
APC105579
(show subtarget assignments)
|
3
|
soluble
|
lpg1976 |
52629304
|
|
UVB-resistance protein UVR8 |
286 |
CONS::PCSEP::Effectors |
4QAM
|
21% |
Legionella pneumophila |
|
|
|
APC105578
(show subtarget assignments)
|
3
|
purified
|
lpg0518 |
52627874
|
|
hypothetical protein |
282 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105577
(show subtarget assignments)
|
3
|
selected
|
lpg1689 |
52629028
|
|
23.7 kDa protein |
208 |
CONS::PCSEP::Effectors |
2MR3
|
13.4% |
Legionella pneumophila |
|
|
|
APC105576
(show subtarget assignments)
|
3
|
expression_tested
|
lpg1483 |
52628824
|
|
serine/threonine-protein kinase |
529 |
CONS::PCSEP::Effectors |
4QOX
|
23.2% |
Legionella pneumophila |
|
|
|
APC105575
(show subtarget assignments)
|
3
|
purified
|
lpg0276 |
52627642
|
|
Ras GEF |
499 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105574
(show subtarget assignments)
|
3
|
selected
|
lpp0759 |
53750513
|
|
hypothetical protein |
203 |
CONS::PCSEP::Effectors |
4LPQ
|
17.3% |
Legionella pneumophila |
|
|
|
APC105573
(show subtarget assignments)
|
3
|
expressed
|
lpg2206 |
52629530
|
|
hypothetical protein |
366 |
CONS::PCSEP::Effectors |
5N6X
|
21.3% |
Legionella pneumophila |
|
|
|
APC105572
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg1621 |
52628960
|
|
hypothetical protein |
439 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105571
(show subtarget assignments)
|
3
|
expressed
|
lpg1408 |
52628749
|
|
choline kinase |
383 |
CONS::PCSEP::Effectors |
3DXQ
|
21.7% |
Legionella pneumophila |
|
|
|
APC105570
(show subtarget assignments)
|
3
|
purified
|
lpg0402 |
52627758
|
|
putative ankyrin-repeat containing prote... |
567 |
CONS::PCSEP::Effectors |
5DNC
|
11.1% |
Legionella pneumophila |
|
|
|
APC105569
(show subtarget assignments)
|
3
|
purified
|
lpg0284 |
52627650
|
|
hypothetical protein |
374 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105568
(show subtarget assignments)
|
9
|
purified
|
lpg0081 |
52627447
|
|
hypothetical protein |
441 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105567
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg1144 |
52628489
|
|
hypothetical protein |
168 |
CONS::PCSEP::Effectors |
2MRN
|
11.9% |
Legionella pneumophila |
|
|
|
APC105566
(show subtarget assignments)
|
3
|
in_pdb
5ES2
|
lpg0634 |
52627982
|
|
hypothetical protein |
449 |
CONS::PCSEP::Effectors |
5JG4
|
99.2% |
Legionella pneumophila |
|
|
|
APC105565
(show subtarget assignments)
|
3
|
expression_tested
|
lpg2999 |
52630303
|
|
astacin protease |
266 |
CONS::PCSEP::Effectors |
3LQ0
|
30.8% |
Legionella pneumophila |
|
|
|
APC105564
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg2591 |
52629908
|
|
hypothetical protein |
165 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105563
(show subtarget assignments)
|
3
|
expression_tested
|
lpp2248 |
53751975
|
|
hypothetical protein |
467 |
CONS::PCSEP::Effectors |
4O60
|
13.3% |
Legionella pneumophila |
|
|
|
APC105562
(show subtarget assignments)
|
3
|
soluble
|
lpg2176 |
52629500
|
|
sphingosine-1-phosphate lyase I |
608 |
CONS::PCSEP::Effectors |
4W8I
|
85.4% |
Legionella pneumophila |
|
|
|
APC105561
(show subtarget assignments)
|
3
|
expressed
|
lpg2131 |
52629456
|
|
ankyrin 3 |
180 |
CONS::PCSEP::Effectors |
3Q9N
|
15% |
Legionella pneumophila |
|
|
|
APC105560
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg0422 |
52627778
|
|
glucoamylase |
449 |
CONS::PCSEP::Effectors |
1AYX
|
31.2% |
Legionella pneumophila |
|
|
|
APC105559
(show subtarget assignments)
|
3
|
expressed
|
lpg1273 |
52628615
|
|
hypothetical protein |
354 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105558
(show subtarget assignments)
|
3
|
cloned
|
lpg0045 |
52627412
|
|
hypothetical protein |
70 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105557
(show subtarget assignments)
|
3
|
expressed
|
lpg0012 |
52627379
|
|
hypothetical protein |
525 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105556
(show subtarget assignments)
|
3
|
purified
|
lpg0898 |
52628244
|
|
hypothetical protein |
243 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105555
(show subtarget assignments)
|
3
|
purified
|
lpg2830 |
52630137
|
|
UBOX-containing protein |
246 |
CONS::PCSEP::Effectors |
4WZ3
|
86.6% |
Legionella pneumophila |
|
|
|
APC105554
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg1966 |
52629294
|
|
hypothetical protein |
521 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105553
(show subtarget assignments)
|
3
|
purified
|
lpg1958 |
52629286
|
|
leucine-rich repeat-containing protein |
542 |
CONS::PCSEP::Effectors |
3GOZ
|
25.6% |
Legionella pneumophila |
|
|
|
APC105552
(show subtarget assignments)
|
3
|
purified
|
lpg1948 |
52629276
|
|
leucine-rich repeat- and coiled coil-con... |
335 |
CONS::PCSEP::Effectors |
3GOZ
|
26.9% |
Legionella pneumophila |
|
|
|
APC105551
(show subtarget assignments)
|
3
|
expressed
|
lpg0515 |
52627871
|
|
phytanoyl-CoA dioxygenase |
310 |
CONS::PCSEP::Effectors |
2OPW
|
26.8% |
Legionella pneumophila |
|
|
|
APC105550
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg1751 |
52629089
|
|
hypothetical protein |
436 |
CONS::PCSEP::Effectors |
4PXT
|
5.7% |
Legionella pneumophila |
|
|
|
APC105549
(show subtarget assignments)
|
3
|
in_pdb
4ZHB
|
lpg0436 |
52627792
|
|
ankyrin repeat-containing protein |
269 |
COMM::UofChicago::Legionella Effectors |
4O60
|
12.3% |
Legionella pneumophila |
|
|
|
APC105548
(show subtarget assignments)
|
3
|
soluble
|
lpg0403 |
52627759
|
|
ankyrin repeat-containing protein |
514 |
CONS::PCSEP::Effectors |
5D68
|
10.7% |
Legionella pneumophila |
|
|
|
APC105547
(show subtarget assignments)
|
3
|
crystallized
|
lpg0096 |
52627462
|
|
hypothetical protein |
397 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105546
(show subtarget assignments)
|
3
|
selected
|
lpg2819 |
52630126
|
|
tyrosine phosphatase II superfamily prot... |
319 |
CONS::PCSEP::Effectors |
4TVV
|
93.7% |
Legionella pneumophila |
|
|
|
APC105545
(show subtarget assignments)
|
3
|
expression_tested
|
lpg2556 |
52629875
|
|
putative protein kinase |
462 |
CONS::PCSEP::Effectors |
3Q5I
|
22.1% |
Legionella pneumophila |
|
|
|
APC105544
(show subtarget assignments)
|
3
|
purified
|
lpg2456 |
52629775
|
|
ankyrin repeat-containing protein |
471 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105543
(show subtarget assignments)
|
3
|
cloned
|
lpg2409 |
52629729
|
|
hypothetical protein |
272 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105542
(show subtarget assignments)
|
3
|
soluble
|
lpp0675 |
53750429
|
|
SidA protein, substrate of the Dot/Icm t... |
474 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105541
(show subtarget assignments)
|
3
|
selected
|
lpg1975 |
52629303
|
|
hypothetical protein |
216 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105540
(show subtarget assignments)
|
3
|
cloned
|
lpg1964 |
52629292
|
|
hypothetical protein |
436 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105539
(show subtarget assignments)
|
3
|
purified
|
lpg1884 |
52629213
|
|
microtubule binding protein, putative |
405 |
CONS::PCSEP::Effectors |
4TQL
|
14.3% |
Legionella pneumophila |
|
|
|
APC105538
(show subtarget assignments)
|
3
|
soluble
|
lpg1701 |
52629040
|
|
kinectin 1 (kinesin receptor) |
560 |
CONS::PCSEP::Effectors |
4MU6
|
65.5% |
Legionella pneumophila |
|
|
|
APC105537
(show subtarget assignments)
|
3
|
expression_tested
|
lpg1660 |
52628999
|
|
leucine-rich repeat-containing protein |
493 |
CONS::PCSEP::Effectors |
4Q62
|
16.6% |
Legionella pneumophila |
|
|
|
APC105536
(show subtarget assignments)
|
3
|
purified
|
lpg0483 |
52627839
|
|
ankyrin repeat-containing protein |
495 |
CONS::PCSEP::Effectors |
5AQ9
|
11.1% |
Legionella pneumophila |
|
|
|
APC105535
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg0294 |
52627660
|
|
hypothetical protein |
230 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
APC105534
(show subtarget assignments)
|
3
|
purified
|
lpg0038 |
52627405
|
|
ankyrin repeat-containing protein |
507 |
CONS::PCSEP::Effectors |
4QFV
|
9.9% |
Legionella pneumophila |
|
|
|
APC105533
(show subtarget assignments)
|
3
|
purified
|
lpg1227 |
52628570
|
|
hypothetical protein |
598 |
CONS::PCSEP::Effectors |
4AKF
|
20.9% |
Legionella pneumophila |
|
|
|
APC105532
(show subtarget assignments)
|
3
|
in_crystallization_trials
|
lpg2509 |
52629828
|
|
SdeD |
397 |
CONS::PCSEP::Effectors |
5BQ9
|
15.9% |
Legionella pneumophila |
|
|
|
APC105531
(show subtarget assignments)
|
3
|
purified
|
lpg2465 |
52629784
|
|
SidD |
507 |
CONS::PCSEP::Effectors |
4IIK
|
61.9% |
Legionella pneumophila |
|
|
|
APC105530
(show subtarget assignments)
|
3
|
soluble
|
lpg2407 |
52629727
|
|
hypothetical protein |
101 |
CONS::PCSEP::Effectors |
|
|
Legionella pneumophila |
|
|
|
